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Collaborations and top research areas from the last five years
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Re-purposing Oncolytic Virotherapy to Re-invigorate CAR T Cell Therapy for Solid Tumors.
Vile, R. G. (PI)
12/1/22 → 11/30/26
Project: Research project
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Mayo Clinic Hepatobiliary SPORE
Mc Niven, M. M. A. (PI), Alberts, S. R. (CoPI), Wang, C. C. (CoPI), Gores, G. J. (CoPI), Leof, E. B. (CoPI), Roberts, L. R. (CoPI), Mandrekar, S. J. (CoPI), Smoot, R. (CoPI), Simon, S. M. (CoPI), Torbenson, M. (CoPI), Vile, R. G. (CoPI) & Yin, V. (CoPI)
9/10/18 → 8/31/26
Project: Research project
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Characterizing the role of CSDE1 as a critical co-factor for VSV replication.
Vile, R. G. (PI)
National Institute of Allergy and Infectious Diseases
3/20/23 → 2/28/26
Project: Research project
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Project 4: Immunovirotherapy
Vile, R. G. (PI) & Vile, R. R. G. (PI)
9/1/19 → 8/31/23
Project: Research project
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Enhancing Therapy of Primary and Recurrent Tumors With Systemic Oncolytic Virus
Vile, R. G. (PI)
5/7/14 → 4/30/19
Project: Research project
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Correction: Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion (Nature Communications, (2025), 16, 1, (4855), 10.1038/s41467-025-60133-5)
Roulstone, V., Kyula-Currie, J., Wright, J., Patin, E. C., Dean, I., Yu, L., Barreiro-Alonso, A., Melake, M., Choudhary, J., Elliott, R., Lord, C. J., Mansfield, D., Matthews, N., Chauhan, R., Jennings, V., Chan Wah Hak, C., Baldock, H., Butera, F., Appleton, E. & Nenclares, P. & 11 others, , Dec 2025, In: Nature communications. 16, 1, 6510.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Exploiting viral infection/vaccination to focus high-affinity T cell populations into tumors using oncolytic viro-immunotherapy
Rios, A. V., Metko, M., Tonne, J., Thompson, J., Kendall, B., Chen, A., Mudrick, H., Masopust, D., Irshad, S., Barry, M., Barry, M. A., Diaz, R. M. & Vile, R., Nov 5 2025, In: Molecular Therapy. 33, 11, p. 5489-5504 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Fusing Oncolytic Virotherapy With Cancer Immunotherapy to Treat Therapy-Resistant Melanoma
Vile, R. G., Nov 22 2025, In: Journal of Clinical Oncology. 24Research output: Contribution to journal › Article › peer-review
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Oncolytic immunovirotherapy: finding the tumor antigen needle in the antiviral haystack
Kendall, B. L. & Vile, R. G., 2025, In: Immunotherapy. 17, 8, p. 585-594 10 p.Research output: Contribution to journal › Review article › peer-review
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Oncolytic viruses as anticancer agents: clinical progress and remaining challenges
Appleton, E., Chiocca, E. A., Ungerechts, G., Melcher, A. & Vile, R., Sep 20 2025, In: The Lancet. 406, 10509, p. 1295-1312 18 p.Research output: Contribution to journal › Review article › peer-review