Projects per year
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Dive into the research topics where Pamela J McLean is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Interrogating alpha-synuclein aggregate-associated proteomes to identify modifiers of Lewy body disease.
McLean, P. J. (PI)
National Institute of Neurological Disorders and Stroke
9/7/26 → 8/31/29
Project: Research project
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Mayo Alzheimer's Disease Research Center
Petersen, R. R. C. (CoPI), Boeve, B. F. (CoPI), Bu, G. D. (CoPI), Knopman, D. S. (CoPI), Dickson, D. W. (CoPI), Jones, D. T. (CoPI), Lucas, J. A. (CoPI), Kantarci, K. M. (CoPI), Kremers, W. K. (CoPI), Petrucelli, L. (CoPI), Ertekin-Taner, N. (CoPI), Petersen, R. C. (CoPI) & McLean, P. J. (CoPI)
7/1/19 → 4/30/27
Project: Research project
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Synergistic Interaction of amyloid-beta and alpha-synuclein in Lewy body Dementia
Dickson, D. W. (PI), Fitzpatrick, A. A. W. (CoPI), Peng, J. J. (CoPI), McLean, P. J. (CoPI) & Ross, O. A. (CoPI)
9/20/19 → 6/30/24
Project: Research project
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Mitochondrial Sirtuin 3 in Parkinson's disease
McLean, P. J. (PI) & Springer, W. (CoPI)
6/1/19 → 5/31/24
Project: Research project
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A split biotin ligase approach reveals proteins associated with oligomeric alpha-synuclein during aggregation
Fernandes, A. R., Owen, A. P., Faroqi, A. H., Lee, J., Sachdeva, G. S., Morderer, D., Hoffmann, C., Madden, B., Zhang, S., Ren, Y., Boschen, S. L., Pandey, A., Rossoll, W. & McLean, P. J., Dec 2026, In: Scientific reports. 16, 1, 7270.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular profiling of alpha-synuclein pathology and seeding activity in Parkinson’s disease
Kaya, Z. B., Amerna, D., Susarla, A., Lim, M. J., Bregendahl, M., Sekiya, H., DeTure, M., Ross, O. A., Dickson, D. W., Boschen, S. L. & McLean, P. J., Jun 2026, In: Acta neuropathologica. 151, 1, 54.Research output: Contribution to journal › Article › peer-review
Open Access -
Pan-neurodegeneration proteomics reveals disease subtypes and molecular signatures
Shrestha, H. K., Sun, H., Yarbro, J. M., Lee, D. G., Liu, D., Wang, E., McReynolds, M., Zhang, N., Xie, B., Yang, S., Yu, K., Poudel, S., Li, Y., Yuan, Z. F., Kong, D., Wang, M., Wang, Z., Niu, M., Wang, H. & Zaman, M. & 27 others, , May 14 2026, In: Cell. 189, 10, p. 3124-3143.e15Research output: Contribution to journal › Article › peer-review
Open Access -
Alpha-synuclein seeding amplification assays in Lewy body dementia: a brief review
Bregendahl, M., Kaya, Z. B., Singer, W. & McLean, P. J., Dec 2025, In: Molecular neurodegeneration. 20, 1, 77.Research output: Contribution to journal › Review article › peer-review
Open Access -
Association between visual hallucinations and α-synuclein oligomers in patients with dementia with Lewy bodies
Sekiya, H., Franke, L., Ono, D., DeTure, M., Ross, O. A., Day, G. S., Lachner, C., Graff-Radford, N. R., McLean, P. J., Ferman, T. J. & Dickson, D. W., Nov 2025, In: Alzheimer's and Dementia. 21, 11, e70904.Research output: Contribution to journal › Article › peer-review
Open Access