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Dive into the research topics where Leonard Petrucelli is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Human Biomarkers Core
Petrucelli, L. (PI)
National Institute of Neurological Disorders and Stroke
9/1/23 → 8/31/26
Project: Research project
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Alzheimer's Disease Tau Core-based Mouse Models and RT-QuiC Biomarker Assay.
Petrucelli, L. (PI)
1/1/21 → …
Project: Research project
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Human Biomarkers Core
Petrucelli, L. (PI) & Petrucelli, L. (PI)
National Institute of Neurological Disorders and Stroke
8/15/21 → 8/31/23
Project: Research project
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The mechanism by which loss of stathmin-2 induces neurodegeneration in ALS
Koike, Y. (PI) & Petrucelli, L. (CoPI)
1/31/21 → 1/30/23
Project: Research project
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Targeted plasma proteomics uncover proteins associated with KIF5A-linked SPG10 and ALS spectrum disorders
Dulski, J., Boddapati, A. K., Risi, B., Iruzubieta, P., Orlacchio, A., Fernández-Torrón, R., Castillo-Triviño, T., López de Munain, A., Vucic, S., Padovani, A., Kaat, L. D., Barakat, T. S., Petrucelli, L., Prudencio, M., Landers, J. E., Weishaupt, J. H., Prokop, A., Filosto, M., Wszolek, Z. K. & Pant, D. C., Jan 15 2026, In: Human Genetics and Genomics Advances. 7, 1, 100498.Research output: Contribution to journal › Article › peer-review
Open Access -
Analysis of the splicing landscape of the frontal cortex in FTLD-TDP reveals subtype specific patterns and cryptic splicing
Faura, J., Heeman, B., Pottier, C., Baker, M. C., DeJesus-Hernandez, M., Küçükali, F., Heiß, L., Wynants, S., Van den Broeck, M., De Rijk, P., De Pooter, T., Joris, G., Finch, N. C. A., Asmann, Y., Strazisar, M., Murray, M. E., Petrucelli, L., Oskarsson, B., Sleegers, K. & Josephs, K. A. & 8 others, , Jun 2025, In: Acta neuropathologica. 149, 1, 59.Research output: Contribution to journal › Article › peer-review
Open Access -
Artificial enforcement of the unfolded protein response reduces disease features in multiple preclinical models of ALS/FTD
Valenzuela, V., Becerra, D., Astorga, J. I., Fuentealba, M., Diaz, G., Bargsted, L., Chacón, C., Martinez, A., Gozalvo, R., Jackson, K., Morales, V., Heras, M. L., Tamburini, G., Petrucelli, L., Sardi, S. P., Plate, L. & Hetz, C., Mar 5 2025, In: Molecular Therapy. 33, 3, p. 1226-1245 20 p.Research output: Contribution to journal › Article › peer-review
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Author Correction: Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration (Nature Aging, (2025), 5, 6, (1143-1158), 10.1038/s43587-025-00878-2)
on behalf of the ALLFTD Consortium, Jul 2025, In: Nature Aging. 5, 7, p. 1372 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Basic Science and Pathogenesis
Petrucelli, L., Dec 1 2025, In: Alzheimer's & dementia : the journal of the Alzheimer's Association. 21, p. e104405Research output: Contribution to journal › Review article › peer-review
Open Access