Laurence J Miller

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Laurence J Miller, MD

1977 …2024

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  • Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling

    Harikumar, K. G., Zhao, P., Cary, B. P., Xu, X., Desai, A. J., Dong, M., Mobbs, J. I., Toufaily, C., Furness, S. G. B., Christopoulos, A., Belousoff, M. J., Wootten, D., Sexton, P. M. & Miller, L. J., Jul 2024, In: PLoS biology. 22, 7 July, e3002673.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Impact of secretin receptor homo-dimerization on natural ligand binding

    Harikumar, K. G., Piper, S. J., Christopoulos, A., Wootten, D., Sexton, P. M. & Miller, L. J., Dec 2024, In: Nature communications. 15, 1, 4390.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Structure-activity relationships of thiadiazole agonists of the human secretin receptor

    Ardecky, R., Dengler, D. G., Harikumar, K. G., Abelman, M. M., Zou, J., Kramer, B. A., Ganji, S. R., Olson, S., Ly, A., Puvvula, N., Ma, C. T., Ramachandra, R., Sergienko, E. A. & Miller, L. J., Sep 2024, In: SLAS Discovery. 29, 6, 100176.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Mechanism of Action and Structure–Activity Relationships of Tetracyclic Small Molecules Acting as Universal Positive Allosteric Modulators of the Cholecystokinin Receptor

    Dengler, D. G., Harikumar, K. G., Yen, A., Sergienko, E. A. & Miller, L. J., Feb 2023, In: Membranes. 13, 2, 150.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

    Alexander, S. P. H., Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A. A., Peters, J. A., Veale, E. L., Armstrong, J. F., Faccenda, E., Harding, S. D., Davies, J. A., Abbracchio, M. P., Abraham, G., Agoulnik, A., Alexander, W., Al-hosaini, K., Bäck, M., Baker, J. G., Barnes, N. M. & Bathgate, R. & 146 others, Beaulieu, J. M., Beck-Sickinger, A. G., Behrens, M., Bernstein, K. E., Bettler, B., Birdsall, N. J. M., Blaho, V., Boulay, F., Bousquet, C., Bräuner-Osborne, H., Burnstock, G., Caló, G., Castaño, J. P., Catt, K. J., Ceruti, S., Chazot, P., Chiang, N., Chini, B., Chun, J., Cianciulli, A., Civelli, O., Clapp, L. H., Couture, R., Cox, H. M., Csaba, Z., Dahlgren, C., Dent, G., Douglas, S. D., Dournaud, P., Eguchi, S., Escher, E., Filardo, E. J., Fong, T., Fumagalli, M., Gainetdinov, R. R., Garelja, M. L., de Gasparo, M., Gerard, C., Gershengorn, M., Gobeil, F., Goodfriend, T. L., Goudet, C., Grätz, L., Gregory, K. J., Gundlach, A. L., Hamann, J., Hanson, J., Hauger, R. L., Hay, D. L., Heinemann, A., Herr, D., Hollenberg, M. D., Holliday, N. D., Horiuchi, M., Hoyer, D., Hunyady, L., Husain, A., IJzerman, A. P., Inagami, T., Jacobson, K. A., Jensen, R. T., Jockers, R., Jonnalagadda, D., Karnik, S., Kaupmann, K., Kemp, J., Kennedy, C., Kihara, Y., Kitazawa, T., Kozielewicz, P., Kreienkamp, H. J., Kukkonen, J. P., Langenhan, T., Larhammar, D., Leach, K., Lecca, D., Lee, J. D., Leeman, S. E., Leprince, J., Li, X. X., Lolait, S. J., Lupp, A., Macrae, R., Maguire, J., Malfacini, D., Mazella, J., McArdle, C. A., Melmed, S., Michel, M. C., Miller, L. J., Mitolo, V., Mouillac, B., Müller, C. E., Murphy, P. M., Nahon, J. L., Ngo, T., Norel, X., Nyimanu, D., O’Carroll, A. M., Offermanns, S., Panaro, M. A., Parmentier, M., Pertwee, R. G., Pin, J. P., Prossnitz, E. R., Quinn, M., Ramachandran, R., Ray, M., Reinscheid, R. K., Rondard, P., Rovati, G. E., Ruzza, C., Sanger, G. J., Schöneberg, T., Schulte, G., Schulz, S., Segaloff, D. L., Serhan, C. N., Singh, K. D., Smith, C. M., Stoddart, L. A., Sugimoto, Y., Summers, R., Tan, V. P., Thal, D., Thomas, W., Timmermans, P. B. M. W. M., Tirupula, K., Toll, L., Tulipano, G., Unal, H., Unger, T., Valant, C., Vanderheyden, P., Vaudry, D., Vaudry, H., Vilardaga, J. P., Walker, C. S., Wang, J. M., Ward, D. T., Wester, H. J., Willars, G. B., Williams, T. L., Woodruff, T. M., Yao, C. & Ye, R. D., Oct 2023, In: British Journal of Pharmacology. 180, S2, p. S23-S144

    Research output: Contribution to journal › Article › peer-review

    Open Access
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