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Projects
- 1 Active
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Poly(ADP-ribose) promotes the condensation and toxicity of C9orf72 arginine-rich dipeptide repeat proteins
Gendron, T. D. (CoPI), Zhang, Y. (CoPI), Zhang, K. (CoPI) & Gendron, T. T. F. (CoPI)
National Institute of Neurological Disorders and Stroke
7/15/21 → 6/30/27
Project: Research project
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PI3K/AKT/mTOR pathway and c-Myc inhibit hepatocyte suspension under simulated microgravity
Xiong, Y., Ma, C., Xie, J., Chen, Z., Zhang, K. & Lei, X. H., Dec 2025, In: npj Microgravity. 11, 1, 88.Research output: Contribution to journal › Article › peer-review
Open Access -
Decoding the interplay between m6A modification and stress granule stability by live-cell imaging
Li, Q., Liu, J., Guo, L., Zhang, Y., Chen, Y., Liu, H., Cheng, H., Deng, L., Qiu, J., Zhang, K., Goh, W. S. S., Wang, Y. & Peng, Q., Nov 15 2024, In: Science Advances. 10, 46, eadp5689.Research output: Contribution to journal › Article › peer-review
Open Access -
c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD
Sahana, T. G., Chase, K. J., Liu, F., Lloyd, T. E., Rossoll, W. & Zhang, K., Apr 26 2023, In: Journal of Neuroscience. 43, 17, p. 3186-3197 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy
Min, Y., Wang, X., Iş, Ö., Patel, T. A., Gao, J., Reddy, J. S., Quicksall, Z. S., Nguyen, T., Lin, S., Tutor-New, F. Q., Chalk, J. L., Mitchell, A. O., Crook, J. E., Nelson, P. T., Van Eldik, L. J., Golde, T. E., Carrasquillo, M. M., Dickson, D. W., Zhang, K. & Allen, M. & 1 others, , Dec 2023, In: Nature communications. 14, 1, 6801.Research output: Contribution to journal › Article › peer-review
Open Access -
Melatonin ameliorates simulated-microgravity-induced mitochondrial dysfunction and lipid metabolism dysregulation in hepatocytes
Xiong, Y., Ma, C., Li, Q., Zhang, W., Zhao, H., Ren, P., Zhang, K. & Lei, X., Sep 2023, In: FASEB Journal. 37, 9, e23132.Research output: Contribution to journal › Article › peer-review