Research output per year
Research output per year
- 1 - 50 out of 56 results
Search results
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2025
Structurally Oriented Classification of FOXA1 Alterations Identifies Prostate Cancers with Opposing Clinical Outcomes and Distinct Molecular and Immunologic Subtypes
Hwang, J., Likasitwatanakul, P., Deshmukh, S. K., Wu, S., Kwon, J. J., Toye, E., Moline, D., Evans, M. G., Elliott, A., Passow, R., Luo, C., John, E., Gandhi, N., McKay, R. R., Heath, E. I., Nabhan, C., Reizine, N., Orme, J. J., Domingo Domenech, J. M. & Sartor, O. & 3 others, , Mar 1 2025, In: Clinical Cancer Research. 31, 5, p. 936-948 13 p.Research output: Contribution to journal › Article › peer-review
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2024
The yin and yang of chromosomal instability in prostate cancer
Carceles-Cordon, M., Orme, J. J., Domingo-Domenech, J. & Rodriguez-Bravo, V., Jun 2024, In: Nature Reviews Urology. 21, 6, p. 357-372 16 p.Research output: Contribution to journal › Review article › peer-review
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2023
Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
Dhital, B., Santasusagna, S., Kirthika, P., Xu, M., Li, P., Carceles-Cordon, M., Soni, R. K., Li, Z., Hendrickson, R. C., Schiewer, M. J., Kelly, W. K., Sternberg, C. N., Luo, J., Lujambio, A., Cordon-Cardo, C., Alvarez-Fernandez, M., Malumbres, M., Huang, H., Ertel, A. & Domingo-Domenech, J. & 1 others, , Feb 21 2023, In: Cell Reports Medicine. 4, 2, 100937.Research output: Contribution to journal › Article › peer-review
Open Access -
Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate Cancer
Santasusagna, S., Zhu, S., Jawalagatti, V., Carceles-Cordon, M., Ertel, A., Garcia-Longarte, S., Song, W. M., Fujiwara, N., Li, P., Mendizabal, I., Petrylak, D. P., Kelly, W. K., Reddy, E. P., Wang, L., Schiewer, M. J., Lujambio, A., Karnes, J., Knudsen, K. E., Cordon-Cardo, C. & Dong, H. & 5 others, , Dec 1 2023, In: Cancer discovery. 13, 12, p. 2584-2609 26 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Rb/e2f1 as a master regulator of cancer cell metabolism in advanced disease
Mandigo, A. C., Yuan, W., Xu, K., Gallagher, P., Pang, A., Guan, Y. F., Shafi, A. A., Thangavel, C., Sheehan, B., Bogdan, D., Paschalis, A., McCann, J. J., Laufer, T. S., Gordon, N., Vasilevskaya, I. A., Dylgjeri, E., Chand, S. N., Schiewer, M. J., Domingo-Domenech, J. & Den, R. B. & 5 others, , Sep 2021, In: Cancer discovery. 11, 9, p. 2334-2353 20 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease
Sato, K., Padgaonkar, A. A., Baker, S. J., Cosenza, S. C., Rechkoblit, O., Subbaiah, D. R. C. V., Domingo-Domenech, J., Bartkowski, A., Port, E. R., Aggarwal, A. K., Ramana Reddy, M. V., Irie, H. Y. & Premkumar Reddy, E., Dec 1 2021, In: Nature communications. 12, 1, 4671.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Cellular rewiring in lethal prostate cancer: the architect of drug resistance
Carceles-Cordon, M., Kelly, W. K., Gomella, L., Knudsen, K. E., Rodriguez-Bravo, V. & Domingo-Domenech, J., May 1 2020, In: Nature Reviews Urology. 17, 5, p. 292-307 16 p.Research output: Contribution to journal › Review article › peer-review
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Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells
Quaglia, F., Krishn, S. R., Daaboul, G. G., Sarker, S., Pippa, R., Domingo-Domenech, J., Kumar, G., Fortina, P., McCue, P., Kelly, W. K., Beltran, H., Liu, Q. & Languino, L. R., Jan 1 2020, In: Journal of Extracellular Vesicles. 9, 1, 1761072.Research output: Contribution to journal › Article › peer-review
Open Access -
Urine Extracellular Vesicle GATA2 mRNA Discriminates Biopsy Result in Men with Suspicion of Prostate Cancer
Woo, J., Santasusagna, S., Banks, J., Pastor-Lopez, S., Yadav, K., Carceles-Cordon, M., Dominguez-Andres, A., Den, R. B., Languino, L. R., Pippa, R., Lallas, C. D., Lu-Yao, G., Kelly, W. K., Knudsen, K. E., Rodriguez-Bravo, V., Tewari, A. K., Prats, J. M., Leiby, B. E., Gomella, L. G. & Domingo-Domenech, J., Oct 1 2020, In: Journal of Urology. 204, 4, p. 691-700 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
EMT- A nd stroma-related gene expression and resistance to pd-1 blockade in urothelial cancer
Wang, L., Saci, A., Szabo, P. M., Chasalow, S. D., Castillo-Martin, M., Domingo-Domenech, J., Siefker-Radtke, A., Sharma, P., Sfakianos, J. P., Gong, Y., Dominguez-Andres, A., Oh, W. K., Mulholland, D., Azrilevich, A., Hu, L., Cordon-Cardo, C., Salmon, H., Bhardwaj, N., Zhu, J. & Galsky, M. D., Sep 2019, In: Journal of Urology. 202, 3, p. 458 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Isolation and characterization of tumor-initiating cells from sarcoma patient-derived xenografts
Han, D., Rodriguez-Bravo, V., Izadmehr, S., Domingo-Domenech, J. & Cordon-Cardo, C., Jun 2019, In: Journal of Visualized Experiments. 2019, 148, e57011.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer
Wang, L., Saci, A., Szabo, P. M., Chasalow, S. D., Castillo-Martin, M., Domingo-Domenech, J., Siefker-Radtke, A., Sharma, P., Sfakianos, J. P., Gong, Y., Dominguez-Andres, A., Oh, W. K., Mulholland, D., Azrilevich, A., Hu, L., Cordon-Cardo, C., Salmon, H., Bhardwaj, N., Zhu, J. & Galsky, M. D., Dec 1 2018, In: Nature communications. 9, 1, 3503.Research output: Contribution to journal › Article › peer-review
Open Access -
Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import
Rodriguez-Bravo, V., Pippa, R., Song, W. M., Carceles-Cordon, M., Dominguez-Andres, A., Fujiwara, N., Woo, J., Koh, A. P., Ertel, A., Lokareddy, R. K., Cuesta-Dominguez, A., Kim, R. S., Rodriguez-Fernandez, I., Li, P., Gordon, R., Hirschfield, H., Prats, J. M., Reddy, E. P., Fatatis, A. & Petrylak, D. P. & 9 others, , Aug 23 2018, In: Cell. 174, 5, p. 1200-1215.e20Research output: Contribution to journal › Article › peer-review
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Phase 2 Trial of Gemcitabine, Cisplatin, plus Ipilimumab in Patients with Metastatic Urothelial Cancer and Impact of DNA Damage Response Gene Mutations on Outcomes
Galsky, M. D., Wang, H., Hahn, N. M., Twardowski, P., Pal, S. K., Albany, C., Fleming, M. T., Starodub, A., Hauke, R. J., Yu, M., Zhao, Q., Sonpavde, G., Donovan, M. J., Patel, V. G., Sfakianos, J. P., Domingo-Domenech, J., Oh, W. K., Akers, N., Losic, B. & Gnjatic, S. & 5 others, , May 2018, In: European urology. 73, 5, p. 751-759 9 p.Research output: Contribution to journal › Article › peer-review
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2017
Generation of prostate cancer cell models of resistance to the anti-mitotic agent docetaxel
Mohr, L., Carceles-Cordon, M., Woo, J., Cordon-Cardo, C., Domingo-Domenech, J. & Rodriguez-Bravo, V., Sep 8 2017, In: Journal of Visualized Experiments. 2017, 127, e56327.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting sarcoma tumor-initiating cells through differentiation therapy
Han, D., Rodriguez-Bravo, V., Charytonowicz, E., Demicco, E., Domingo-Domenech, J., Maki, R. G. & Cordon-Cardo, C., May 1 2017, In: Stem Cell Research. 21, p. 117-123 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The role of GATA2 in lethal prostate cancer aggressiveness
Rodriguez-Bravo, V., Carceles-Cordon, M., Hoshida, Y., Cordon-Cardo, C., Galsky, M. D. & Domingo-Domenech, J., Jan 1 2017, In: Nature Reviews Urology. 14, 1, p. 38-48 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma
Tovar, V., Cornella, H., Moeini, A., Vidal, S., Hoshida, Y., Sia, D., Peix, J., Cabellos, L., Alsinet, C., Torrecilla, S., Martinez-Quetglas, I., Lozano, J. J., Desbois-Mouthon, C., Solé, M., Domingo-Domenech, J., Villanueva, A. & Llovet, J. M., Mar 1 2017, In: Gut. 66, 3, p. 530-540 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Definitive management of primary bladder tumors in the context of metastatic disease: Who, how, when, and why?
Galsky, M. D., Domingo-Domenech, J., Sfakianos, J. P. & Ferket, B. S., Oct 10 2016, In: Journal of Clinical Oncology. 34, 29, p. 3495-3498 4 p.Research output: Contribution to journal › Article › peer-review
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Development of target specific agents for bladder cancer
Domingo-Domenech, J., Niglio, S. & Galsky, M. D., Jul 3 2016, In: Expert Review of Precision Medicine and Drug Development. 1, 4, p. 361-368 8 p.Research output: Contribution to journal › Review article › peer-review
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Enrichment of Cells with Cancer Stem Cell-Like Markers in Relapses of Chemoresistant Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma
Grau, J. J., Mesía, R., De La Iglesia-Vicente, M., Williams, E. S., Taberna, M., Caballero, M., Larque, A. B., De La Oliva, J., Cordón-Cardo, C. & Domingo-Domenech, J., May 1 2016, In: Oncology (Switzerland). 90, 5, p. 267-272 6 p.Research output: Contribution to journal › Article › peer-review
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2015
A Targetable GATA2-IGF2 Axis Confers Aggressiveness in Lethal Prostate Cancer
Vidal, S. J., Rodriguez-Bravo, V., Quinn, S. A., Rodriguez-Barrueco, R., Lujambio, A., Williams, E., Sun, X., delaIglesia-Vicente, J., Lee, A., Readhead, B., Chen, X., Galsky, M., Esteve, B., Petrylak, D. P., Dudley, J. T., Rabadan, R., Silva, J. M., Hoshida, Y., Lowe, S. W. & Cordon-Cardo, C. & 1 others, , Feb 9 2015, In: Cancer cell. 27, 2, p. 223-239 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Generation of prostate cancer patient derived xenograft models from circulating tumor cells
Williams, E. S., Rodriquez-Bravo, V., Chippada-Venkata, U., De Ia Iglesia-Vicente, J., Gong, Y., Galsky, M., Oh, W., Cordon-Cardo, C. & Domingo-Domenech, J., Oct 20 2015, In: Journal of Visualized Experiments. 2015, 104, e53182.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
Isolation of cancer stem cells from human prostate cancer samples
Vidal, S. J., Aidan Quinn, S., de la Iglesia-Vicente, J., Bonal, D. M., Rodriguez-Bravo, V., Firpo-Betancourt, A., Cordon-Cardo, C. & Domingo-Domenech, J., Mar 14 2014, In: Journal of Visualized Experiments. 85, e51332.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting cancer stem cells to suppress acquired chemotherapy resistance
Vidal, S. J., Rodriguez-Bravo, V., Galsky, M., Cordon-Cardo, C. & Domingo-Domenech, J., Sep 4 2014, In: Oncogene. 33, 36, p. 4451-4463 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
2013
A common MicroRNA signature consisting of miR-133a, miR-139-3p, and miR-142-3p clusters bladder carcinoma in situ with normal umbrella cells
Jia, A. Y., Castillo-Martin, M., Domingo-Domenech, J., Bonal, D. M., Sánchez-Carbayo, M., Silva, J. M. & Cordon-Cardo, C., Apr 2013, In: American Journal of Pathology. 182, 4, p. 1171-1179 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Advances in the management of muscle-invasive bladder cancer through risk prediction, risk communication, and novel treatment approaches
Galsky, M. D. & Domingo-Domenech, J., Feb 2013, In: Clinical Advances in Hematology and Oncology. 11, 2, p. 86-92 7 p.Research output: Contribution to journal › Article › peer-review
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2012
A bac-based transgenic mouse specifically expresses an inducible cre in the urothelium
Shen, T. H., Gladoun, N., Castillo-Martin, M., Bonal, D., Domingo-Domenech, J., Charytonowicz, D. & Cordon-Cardo, C., Apr 9 2012, In: PloS one. 7, 4, e35243.Research output: Contribution to journal › Article › peer-review
Open Access -
PAX7-FKHR fusion gene inhibits myogenic differentiation via NF-kappaB upregulation
Charytonowicz, E., Matushansky, I., Domingo-Doménech, J., Castillo-Martín, M., Ladanyi, M., Cordon-Cardo, C. & Ziman, M., Mar 2012, In: Clinical and Translational Oncology. 14, 3, p. 197-206 10 p.Research output: Contribution to journal › Article › peer-review
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Suppression of Acquired Docetaxel Resistance in Prostate Cancer through Depletion of Notch- and Hedgehog-Dependent Tumor-Initiating Cells
Domingo-Domenech, J., Vidal, S. J., Rodriguez-Bravo, V., Castillo-Martin, M., Quinn, S. A., Rodriguez-Barrueco, R., Bonal, D. M., Charytonowicz, E., Gladoun, N., de la Iglesia-Vicente, J., Petrylak, D. P., Benson, M. C., Silva, J. M. & Cordon-Cardo, C., Sep 11 2012, In: Cancer cell. 22, 3, p. 373-388 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2011
Anatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
Reis, L. O., Sopena, J. M. G., Fávaro, W. J., Martin, M. C., Simão, A. F. L., dos Reis, R. B., de Andrade, M. F., Domenech, J. D. & Cardo, C. C., 2011, In: Acta Cirurgica Brasileira. 26, SUPPL. 2, p. 106-110 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression
Karni-Schmidt, O., Castillo-Martin, M., HuaiShen, T., Gladoun, N., Domingo-Domenech, J., Sanchez-Carbayo, M., Li, Y., Lowe, S., Prives, C. & Cordon-Cardo, C., Mar 2011, In: American Journal of Pathology. 178, 3, p. 1350-1360 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Indicaciones de la radioterapia en el cáncer de piel, melanoma
Translated title of the contribution :Role of radiotherapy in skin cancer melanoma Research output: Contribution to journal › Article › peer-review
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Predictive value of microtubule associated proteins tau and stathmin in patients with nonmuscle invasive bladder cancer receiving adjuvant intravesical taxane therapy
Wosnitzer, M. S., Domingo-Domenech, J., Castillo-Martin, M., Ritch, C., Mansukhani, M., Petrylack, D. P., Benson, M. C., McKiernan, J. M. & Cordon-Cardo, C., Nov 2011, In: Journal of Urology. 186, 5, p. 2094-2100 7 p.Research output: Contribution to journal › Article › peer-review
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2010
Molecular pathways of urothelial development and bladder tumorigenesis
Castillo-Martin, M., Domingo-Domenech, J., Karni-Schmidt, O., Matos, T. & Cordon-Cardo, C., 2010, In: Urologic Oncology: Seminars and Original Investigations. 28, 4, p. 401-408 8 p.Research output: Contribution to journal › Review article › peer-review
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2009
Loco-regional control after postoperative radiotherapy for patients with regional nodal metastases from melanoma
Conill, C., Valduvieco, I., Domingo-Domènech, J., Arguis, P., Vidal-Sicart, S. & Vilalta, A., Oct 2009, In: Clinical and Translational Oncology. 11, 10, p. 688-693 6 p.Research output: Contribution to journal › Article › peer-review
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2008
Dihydropyrimidine dehydrogenases and cytidine-deaminase gene polymorphisms as outcome predictors in resected gastric cancer patients treated with fluoropyrimidine adjuvant chemotherapy
Grau, J. J., Caballero, M., Monzó, M., Muñoz-García, C., Domingo-Domenech, J., Navarro, A., Conill, C., Campayo, M. & Bombí, J. A., Aug 1 2008, In: Journal of Surgical Oncology. 98, 2, p. 130-134 5 p.Research output: Contribution to journal › Article › peer-review
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Inactivation of NF-κB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells
Domingo-Domènech, J., Pippa, R., Tápia, M., Gascón, P., Bachs, O. & Bosch, M., Nov 2008, In: Breast Cancer Research and Treatment. 112, 1, p. 53-62 10 p.Research output: Contribution to journal › Article › peer-review
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Serum HER2 extracellular domain predicts an aggressive clinical outcome and biological PSA response in hormone-independent prostate cancer patients treated with docetaxel
Domingo-Domenech, J., Fernandez, P. L., Filella, X., Martinez-Fernandez, A., Molina, R., Fernandez, E., Alcaraz, A., Codony, J., Gascon, P. & Mellado, B., Feb 2008, In: Annals of Oncology. 19, 2, p. 269-275 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2007
Clinical outcome after surgical resection of lung metastases from melanoma
Conilla, C., Gimferrer, J. M., Marruecos, J., Domingo-Domènech, J., Vilella, R., Catalán, M., Malvehy, J., Puig, S. & Castel, T., 2007, In: Clinical and Translational Oncology. 9, 1, p. 48-52 5 p.Research output: Contribution to journal › Article › peer-review
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Clinical outcome in patients with intramedullary spinal cord metastases from lung cancer
Conill, C., Marruecos, J., Verger, E., Berenguer, J., Lomeña, F., Domingo-Domènech, J., Grau, J. J. & Casas, F., 2007, In: Clinical and Translational Oncology. 9, 3, p. 172-176 5 p.Research output: Contribution to journal › Article › peer-review
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Prognostic implications of protein S-100β serum levels in the clinical outcome of high-risk melanoma patients
Domingo-Domènech, J., Castel, T., Auge, J. M., Garcia-Albeniz, X. A., Conill, C., Puig, S., Vilella, R., Matas, J., Malvehy, J., Gascón, P., Mellado, B. & Molina, R., Nov 2007, In: Tumor Biology. 28, 5, p. 264-272 9 p.Research output: Contribution to journal › Article › peer-review
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Serum vascular endothelial growth factor as a predictive factor in metronomic (weekly) paclitaxel treatment for advanced head and neck cancer
Caballero, M., Grau, J. J., Blanch, J. L., Domingo-Domenech, J., Auge, J. M., Jimenez, W. & Bernal-Sprekelsen, M., Nov 2007, In: Archives of Otolaryngology - Head and Neck Surgery. 133, 11, p. 1143-1148 6 p.Research output: Contribution to journal › Article › peer-review
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Toxicity of combined treatment of adjuvant irradiation and interferon α2b in high-risk melanoma patients
Conill, C., Jorcano, S., Domingo-Domènech, J., Marruecos, J., Vilella, R., Malvehy, J., Puig, S., Sánchez, M., Gallego, R. & Castel, T., Oct 2007, In: Melanoma research. 17, 5, p. 304-309 6 p.Research output: Contribution to journal › Review article › peer-review
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2006
Differential cellular and molecular effects of bortezomib, a proteasome inhibitor, in human breast cancer cells
Codony-Servat, J., Tapia, M. A., Bosch, M., Oliva, C., Domingo-Domenech, J., Mellado, B., Rolfe, M., Ross, J. S., Gascon, P., Rovira, A. & Albanell, J., Mar 2006, In: Molecular cancer therapeutics. 5, 3, p. 665-675 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Interleukin 6, a nuclear factor-κB target, predicts resistance to docetaxel in hormone-independent prostate cancer and nuclear factor-κB inhibition by PS-1145 enhances docetaxel antitumor activity
Domingo-Domenech, J., Oliva, C., Rovira, A., Codony-Servat, J., Bosch, M., Filella, X., Montagut, C., Tapia, M., Campás, C., Dang, L., Rolfe, M., Ross, J. S., Gascon, P., Albanell, J. & Mellado, B., Sep 15 2006, In: Clinical Cancer Research. 12, 18, p. 5578-5586 9 p.Research output: Contribution to journal › Article › peer-review
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Time-related improvement of survival in resectable gastric cancer: The role of Japanese-style gastrectomy with D2 lymphadenectomy and adjuvant chemotheraphy
Grau, J. J., Palmero, R., Marmol, M., Domingo-Domenech, J., Monzo, M., Fuster, J., Vidal, O., Fondevila, C. & Garcia-Valdecasas, J. C., Aug 11 2006, In: World Journal of Surgical Oncology. 4, 53.Research output: Contribution to journal › Article › peer-review
Open Access -
Whole brain irradiation and temozolomide based chemotherapy in melanoma brain metastases
Conill, C., Jorcano, S., Domingo-Doménech, J., Gallego, R., Malvehy, J., Puig, S., Sánchez, M., Vilella, R. & Castel, T., 2006, In: Clinical and Translational Oncology. 8, 4, p. 266-270 5 p.Research output: Contribution to journal › Article › peer-review
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2005
Activation of nuclear factor-κB in human prostate carcinogenesis and association to biochemical relapse
Domingo-Domenech, J., Mellado, B., Ferrer, B., Truan, D., Codony-Servat, J., Sauleda, S., Alcover, J., Campo, E., Gascon, P., Rovira, A., Ross, J. S., Fernández, P. L. & Albanell, J., Nov 28 2005, In: British journal of cancer. 93, 11, p. 1285-1294 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Pro-gastrin-releasing peptide (ProGRP) in patients with benign and malignant diseases: Comparison with CEA, SCC, CYFRA 21-1 and NSE in patients with lung cancer
Molina, R., Auge, J. M., Filella, X., Viñolas, N., Alicarte, J., Domingo, J. M. & Ballesta, A. M., May 2005, In: Anticancer research. 25, 3 A, p. 1773-1778 6 p.Research output: Contribution to journal › Article › peer-review