Projects per year
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Collaborations and top research areas from the last five years
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Antibody Drug Conjugate Designs to Enhance the Therapeutic Window for Brain Tumors
Sarkaria, J. N. (PI) & Tsuchikama, K. K. (CoPI)
National Institute of Neurological Disorders and Stroke
8/1/25 → 4/30/26
Project: Research project
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Maximizing the efficacy of MDM2 inhibitor therapy for MDM2-amplified glioblastoma
Sarkaria, J. N. (PI)
8/1/24 → 7/31/26
Project: Research project
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Quantitative systems biology of glioblastoma cells and their interactions with the neuronal and immunological milieu
Lauffenburger, D. A. (PI), Michor, F. (CoPI), Sarkaria, J. N. (CoPI), Agar, N. Y. R. (CoPI) & Spranger, S. S. (CoPI)
9/15/23 → 8/31/26
Project: Research project
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Development of the brain penetrant ATM inhibitor WSD0628 in combination with radiation for recurrent high grade glioma
Sarkaria, J. N. (PI)
U.S. Food and Drug Administration
9/10/23 → 5/31/26
Project: Research project
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Digital twins for in vivo metabolic flux estimations in patients with brain cancer
Meghdadi, B., Al-Holou, W. N., Scott, A. J., Mittal, A., Liang, N., Sravya, P., Achreja, A., O’Brien, A., Do, K., Wu, Z., Feng, J., Qi, N. R., Tarnal, V., Venneti, S., Miller, C. R., Sarkaria, J. N., Zhou, W., Lawrence, T. S., Lyssiotis, C. A. & Wahl, D. R. & 1 others, , Jan 6 2026, In: Cell Metabolism. 38, 1, p. 228-246.e17Research output: Contribution to journal › Article › peer-review
Open Access -
A field resource for the glioma cerebrospinal fluid proteome: Impacts of resection and location on biomarker discovery
Riviere-Cazaux, C., Graser, C. J., Warrington, A. E., Hoplin, M. D., Andersen, K. M., Malik, N., Palmer, E. A., Carlstrom, L. P., Dasari, S., Munoz-Casabella, A., Ikram, S., Ghadimi, K., Himes, B. T., Jusue-Torres, I., Sarkaria, J. N., Meyer, F. B., Van Gompel, J. J., Kizilbash, S. H., Sener, U. & Michor, F. & 3 others, , Apr 1 2025, In: Neuro-oncology. 27, 4, p. 948-962 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Analysis of imaging signatures in 18F-DOPA PET of glioblastoma treated with dose-escalated radiotherapy
Qian, J., Pafundi, D. H., Breen, W. G., Brown, P. D., Hunt, C. H., Jacobson, M. S., Johnson, D. R., Kaufmann, T. J., Kemp, B. J., Kizilbash, S. H., Lowe, V. J., Ruff, M. W., Sarkaria, J. N., Uhm, J. H., Zakhary, M. J., Seaberg, M. H., Wan Chan Tseung, H. S., Yan, E. S., Zhang, Y. & Laack, N. N. & 1 others, , 2025, In: Frontiers in Oncology. 15, 1623313.Research output: Contribution to journal › Article › peer-review
Open Access -
Correction to: EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180 (Oncogene, (2014), 33, 19, (2504-2512), 10.1038/onc.2013.198)
Feng, H., Hu, B., Vuori, K., Sarkaria, J. N., Furnari, F. B., Cavenee, W. K. & Cheng, S. Y., Mar 24 2025, In: Oncogene. 44, 10, p. 710-711 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
DNA-PK Inhibition Shows Differential Radiosensitization in Orthotopic GBM PDX Models Based on DDR Pathway Deficits
Dragojevic, S., Smith, E. J., Regan, M. S., Stopka, S. A., Baquer, G., Xue, Z., Zhang, W., Connors, M. A., Kloeber, J. A., Hu, Z., Bakken, K. K., Ott, L. L., Carlson, B. L., Burgenske, D. M., Decker, P. A., Tian, S., Gupta, S. K., Laverty, D. J., Eckel-Passow, J. E. & Elmquist, W. F. & 4 others, , Jun 1 2025, In: Molecular cancer therapeutics. 24, 6, p. 859-869 11 p.Research output: Contribution to journal › Article › peer-review
Open Access