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Dive into the research topics where James L Kirkland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Los Angeles Claude D. Pepper Older Americans Independence Center
Espinoza, S. (PI), Kirkland, J. L. (CoPI), Moore, J. J. H. (CoPI), Wanagat, J. J. (CoPI), Gonzales, M. M. (CoPI), Musi, N. N. (CoPI), Cohen, P. P. (CoPI) & Cheng, S. S. (CoPI)
9/1/25 → 8/31/26
Project: Research project
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Resource Core 1 (RC1) Advanced Gerotherapeutics
Kirkland, J. L. (PI)
7/1/25 → 6/30/26
Project: Research project
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Translational Geroscience Network
Kirkland, J. L. (PI), Kuchel, G. G. A. (CoPI), Kritchevsky, S. S. B. (CoPI), Tchkonia, T. (CoPI), Kirkland, J. J. L. (CoPI) & Pignolo, R. R. J. (CoPI)
2/1/19 → 6/30/26
Project: Research project
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Sen-Survivors: An open-label intervention trial for frailty and senescence
Armstrong, G. (PI) & Kirkland, J. L. (CoPI)
9/1/20 → 8/31/23
Project: Research project
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Senescence cells as a source of pro-aging miR-146a
Masternak, M. M. (PI) & Kirkland, J. L. (CoPI)
9/1/19 → 8/31/20
Project: Research project
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Early and Late Myocardial Effects of Proton Beam Cardiac Radioablation: Insights From Gene Expression Analysis
Hirao, T., Suda, M., Rettmann, M. E., Deisher, A. J., Wight, J. A., Koya, T., Newman, L. K., Tchkonia, T., Kruse, J. J., Shumway, D. A., Merrell, K. W., Asirvatham, S. J., Kirkland, J. L., Packer, D. L. & Siontis, K. C., 2026, (Accepted/In press) In: JACC: Clinical Electrophysiology.Research output: Contribution to journal › Article › peer-review
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Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers
Tripathi, U., Suda, M., Kulshreshtha, V., Piatkowski, B. T., Palmer, A. K., Giorgadze, N., Inman, C., Gasek, N., Xu, M., Johnson, K. O., Pirtskhalava, T., Chaib, S., Langhi Prata, L. P. G., Zhu, Y., Kandhaya-Pillai, R., Tullius, S. G., Wyles, S. P., Majji, R., Yalamanchili, H. K. & Allison, D. B. & 2 others, , Jan 2026, In: Aging Cell. 25, 1, e70358.Research output: Contribution to journal › Article › peer-review
Open Access -
Senotherapeutics for metabolic disease and diabetic complications
Palmer, A. K., Spinelli, R., Prata, L. G. L., Chaib, S., Suda, M., Tchkonia, T., Smith, U. & Kirkland, J. L., Jan 2026, In: Journal of Internal Medicine. 299, 1, p. 2-19 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Spatial Reorganization of Chromatin Architecture Shapes the Expression Phenotype of Therapy-Induced Senescent Cells
Zhang, G., Zhang, W., Wang, C., Jiang, Z., Xu, Q., Li, H., Kirkland, J. L., Wei, G. & Sun, Y., Jan 2026, In: Aging Cell. 25, 1, e70366.Research output: Contribution to journal › Article › peer-review
Open Access -
Translating cellular senescence research into clinical practice for metabolic disease
Chaib, S., Palmer, A. K., Wyles, S. P., Musi, N., Kirkland, J. L. & Tchkonia, T., Feb 2026, In: Nature Reviews Endocrinology. 22, 2, p. 102-115 14 p.Research output: Contribution to journal › Review article › peer-review