Projects per year
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Dive into the research topics where Guojun D Bu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Biology and pathobiology of apoE in aging and Alzheimer's disease
Kanekiyo, T. (PI), Asmann, Y. W. (CoPI), Asmann, Y. W. (CoPI), Karch, C. C. M. (CoPI), Liu, C.-C. (CoPI), Bu, G. D. (CoPI), Karch, C. C. M. (CoPI), Liu, C.-C. C. (CoPI), Holtzman, D. D. M. (CoPI), Dickson, D. D. W. (CoPI), Peng, J. J. (CoPI) & Asmann, Y. (CoPI)
6/1/21 → 5/31/26
Project: Research project
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Administrative Core
Bu, G. D. (PI), Bu, G. G. (PI) & Kanekiyo, T. (PI)
3/1/21 → 5/31/26
Project: Research project
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Human iPSC Models Core
Bu, G. D. (PI), Bu, G. G. (PI) & Karch, C. C. M. (PI)
2/1/21 → 5/31/26
Project: Research project
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Impact of vascular apoE in aging and AD
Bu, G. D. (PI), Bu, G. G. (PI) & Kanekiyo, T. (PI)
2/1/21 → 5/31/26
Project: Research project
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Mayo Alzheimer's Disease Research Center
Boeve, B. B. F. (PI), Bu, G. D. (CoPI), Dickson, D. W. (CoPI), Jones, D. T. (CoPI), Kantarci, K. M. (CoPI), Knopman, D. S. (CoPI), Kremers, W. K. (CoPI), Petrucelli, L. (CoPI), Lucas, J. A. (CoPI), Ertekin-Taner, N. (CoPI), McLean, P. J. (CoPI) & Petersen, R. R. C. (CoPI)
7/1/19 → 4/30/26
Project: Research project
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Alzheimer's disease risk ABCA7 p.A696S variant disturbs the microglial response to amyloid pathology in mice
Ma, X., Prokopenko, D., Wang, N., Aikawa, T., Choi, Y., Zhang, C., Lei, D., Ren, Y., Kawatani, K., Starling, S. C., Perkerson, R. B., Roy, B., Quintero, A. C., Parsons, T. M., Pan, Y., Li, Z., Wang, M., Bao, H., Han, X. & Bu, G. & 2 others, , Mar 2025, In: Neurobiology of Disease. 206, 106813.Research output: Contribution to journal › Article › peer-review
Open Access -
Amyloid pathology and cognitive impairment in hAβ-KI and APPSAA-KI mouse models of Alzheimer's disease
Lu, W., Shue, F., Kurti, A., Jeevaratnam, S., Macyczko, J. R., Roy, B., Izhar, T., Wang, N., Bu, G., Kanekiyo, T. & Li, Y., Jan 2025, In: Neurobiology of aging. 145, p. 13-23 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A p16 pathway to prevention: Senescence as a driver of tau-mediated neurodegeneration
Lam, J. Y. L., Wang, K. & Bu, G., Jul 23 2025, In: Neuron. 113, 14, p. 2215-2217 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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APOE genotype determines cell-type-specific pathological landscape of Alzheimer's disease
Li, Z., Martens, Y. A., Ren, Y., Jin, Y., Sekiya, H., Doss, S. V., Kouri, N., Castanedes-Casey, M., Christensen, T. A., Miller Nevalainen, L. B., Takegami, N., Chen, K., Liu, C. C., Soto-Beasley, A., Boon, B. D. C., Labuzan, S. A., Ikezu, T. C., Chen, Y., Bartkowiak, A. D. & Xhafkollari, G. & 10 others, , May 7 2025, In: Neuron. 113, 9, p. 1380-1397.e7Research output: Contribution to journal › Article › peer-review
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APOE genotype influences on the brain metabolome of aging mice – role for mitochondrial energetics in mechanisms of resilience in APOE2 genotype
the Alzheimer’s Disease Metabolomics Consortium, Dec 2025, In: Molecular neurodegeneration. 20, 1, 97.Research output: Contribution to journal › Article › peer-review
Open Access