Fergus J Couch

2023

Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry

NBCS Collaborators, CTS Consortium & ABCTB Investigators, Dec 2023, In: Genome medicine. 15, 1, 7.

Research output: Contribution to journal › Article › peer-review

Open Access

Association of raloxifene and tamoxifen therapy with cognitive performance, odds of mild cognitive impairment, and brain MRI markers of neurodegeneration

Kara, F., Lohse, C. M., Castillo, A. M., Tosakulwong, N., Lesnick, T. G., Jack, C. R., Petersen, R. C., Olson, J. E., Couch, F. J., Ruddy, K. J., Kantarci, K. & Mielke, M. M., Feb 2023, In: Cancer medicine. 12, 3, p. 2805-2817 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival

Lopes Cardozo, J. M. N., Andrulis, I. L., Bojesen, S. E., Dörk, T., Eccles, D. M., Fasching, P. A., Hooning, M. J., Keeman, R., Nevanlinna, H., Rutgers, E. J. T., Easton, D. F., Hall, P., Pharoah, P. D. P., Van 't Veer, L. J., Schmidt, M. K., Ahearn, T. U., Anton-Culver, H., Arndt, V., Auer, P. L., Augustinsson, A., & 147 othersBeane Freeman, L. E., Becher, H., Beckmann, M. W., Behrens, S., Benitez, J., Bermisheva, M., Blomqvist, C., Bolla, M. K., Bonanni, B., Boyle, T., Brenner, H., Brucker, S. Y., Brüning, T., Burwinkel, B., Buys, S. S., Camp, N. J., Canzian, F., Cardoso, F., Castelao, J. E., Cessna, M. H., Chan, T. L., Chang-Claude, J., Chenevix-Trench, G., Choi, J. Y., Colonna, S. V., Copson, E., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Dennis, J., Devilee, P., Drukker, C. A., Dunning, A. M., Dwek, M., Eliassen, A. H., Engel, C., Evans, D. G., Figueroa, J. D., Fletcher, O., Flyger, H., Gago-Dominguez, M., García-Closas, M., García-Sáenz, J. A., Genkinger, J., Giles, G. G., González-Neira, A., Guénel, P., Gündert, M., Hahnen, E., Haiman, C. A., Håkansson, N., Hamann, U., Hartman, M., Heemskerk-Gerritsen, B. A. M., Hein, A., Ho, W. K., Hoppe, R., Hopper, J. L., Houlston, R. S., Howell, A., Hunter, D. J., Ito, H., Jakubowska, A., Jernström, H., John, E. M., Johnson, N., Jones, M. E., Joseph, V., Kaaks, R., Kang, D., Kim, S. W., Kitahara, C. M., Koppert, L. B., Kosma, V. M., Kraft, P., Kristensen, V. N., Kubelka-Sabit, K., Koutros, S., Kurian, A. W., Kwong, A., Lacey, J. V., Lambrechts, D., Le Marchand, L., Li, J., Lubiński, J., Lush, M., Mannermaa, A., Manoochehri, M., Margolin, S., Matsuo, K., Mavroudis, D., Michailidou, K., Milne, R. L., Mohd Taib, N. A., Mulligan, A. M., Neven, P., Newman, W. G., Obi, N., Offit, K., Olshan, A. F., Park, S. K., Park-Simon, T. W., Patel, A. V., Plaseska-Karanfilska, D., Poncet, C., Prentice, R. L., Presneau, N., Prevos, R., Pylkäs, K., Radice, P., Rennert, G., Rennert, H. S., Romero, A., Saloustros, E., Sawyer, E. J., Schmutzler, R. K., Schwentner, L., Scott, C., Shah, M., Shen, C. Y., Shu, X. O., Sim, X., Southey, M. C., Stone, J., Stram, D. O., Tamimi, R. M., Teo, S. H., Teras, L. R., Terry, M. B., Tomczyk, K., Tomlinson, I., Troester, M. A., Truong, T., Vachon, C. M., Van Ongeval, C., Wang, Q., Wappenschmidt, B., Wendt, C., Winqvist, R., Wolk, A., Wu, A. H., Yadav, S., Yip, C. H., Zheng, W. & Ziogas, A., Apr 1 2023, In: Journal of Clinical Oncology. 41, 10, p. 1849-1863 15 p.

Research output: Contribution to journal › Article › peer-review

BRCA1 frameshift variants leading to extended incorrect protein C termini

Nepomuceno, T. C., Foo, T. K., Richardson, M. E., Ranola, J. M. O., Weyandt, J., Varga, M. J., Alarcon, A., Gutierrez, D., von Wachenfeldt, A., Eriksson, D., Kim, R., Armel, S., Iversen, E., Couch, F. J., Borg, Å., Xia, B., Carvalho, M. A. & Monteiro, A. N. A., Oct 12 2023, In: Human Genetics and Genomics Advances. 4, 4, 100240.

Research output: Contribution to journal › Article › peer-review

Open Access

Changes in amount and intensity of physical activity over time in breast cancer survivors

Marell, P. S., Vierkant, R. A., Olson, J. E., Herrmann, J., Larson, N. L., LeBrasseur, N. K., D'Andre, S. D., Ehlers, D. K., Stan, D. L., Cheville, A. L., Barksdale, T., Loprinzi, C. L., Couch, F. J. & Ruddy, K. J., Oct 1 2023, In: JNCI Cancer Spectrum. 7, 5, pkad056.

Research output: Contribution to journal › Article › peer-review

Open Access

Clinical outcomes and prognostic factors in triple-negative invasive lobular carcinoma of the breast

Joshi, U., Budhathoki, P., Gaire, S., Yadav, S. K., Shah, A., Adhikari, A., Choong, G., Couzi, R., Giridhar, K. V., Leon-Ferre, R. A., Boughey, J. C., Hieken, T. J., Mutter, R., Ruddy, K. J., Haddad, T. C., Goetz, M. P., Couch, F. J. & Yadav, S., Jul 2023, In: Breast Cancer Research and Treatment. 200, 2, p. 217-224 8 p.

Research output: Contribution to journal › Article › peer-review

Contralateral Breast Cancer Risk among Carriers of Germline Pathogenic Variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2

Yadav, S., Boddicker, N. J., Na, J., Polley, E. C., Hu, C., Hart, S. N., Gnanaolivu, R. D., Larson, N., Holtegaard, S., Huang, H., Dunn, C. A., Teras, L. R., Patel, A. V., Lacey, J. V., Neuhausen, S. L., Martinez, E., Haiman, C., Chen, F., Ruddy, K. J., Olson, J. E., & 16 othersJohn, E. M., Kurian, A. W., Sandler, D. P., O'Brien, K. M., Taylor, J. A., Weinberg, C. R., Anton-Culver, H., Ziogas, A., Zirpoli, G., Goldgar, D. E., Palmer, J. R., Domchek, S. M., Weitzel, J. N., Nathanson, K. L., Kraft, P. & Couch, F. J., Mar 20 2023, In: Journal of Clinical Oncology. 41, 9, p. 1703-1713 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Distinct spatial immune microlandscapes are independently associated with outcomes in triple-negative breast cancer

Carter, J. M., Chumsri, S., Hinerfeld, D. A., Ma, Y., Wang, X., Zahrieh, D., Hillman, D. W., Tenner, K. S., Kachergus, J. M., Brauer, H. A., Warren, S. E., Henderson, D., Shi, J., Liu, Y., Joensuu, H., Lindman, H., Leon-Ferre, R. A., Boughey, J. C., Liu, M. C., Ingle, J. N., & 6 othersKalari, K. R., Couch, F. J., Knutson, K. L., Goetz, M. P., Perez, E. A. & Thompson, E. A., Dec 2023, In: Nature communications. 14, 1, 2215.

Research output: Contribution to journal › Article › peer-review

Open Access

Financial hardship in breast cancer survivors: a prospective analysis of change in financial concerns over time

Storandt, M. H., Durani, U., Stan, D., Larson, N., Loprinzi, C., Couch, F., Olson, J. E., Khera, N. & Ruddy, K. J., Jan 2023, In: Supportive Care in Cancer. 31, 1, 62.

Research output: Contribution to journal › Article › peer-review

Germline Mutations in 12 Genes and Risk of Ovarian Cancer in Three Population-Based Cohorts

Kotsopoulos, J., Hathaway, C. A., Narod, S. A., Teras, L. R., Patel, A. V., Hu, C., Yadav, S., Couch, F. J. & Tworoger, S. S., Oct 1 2023, In: Cancer Epidemiology Biomarkers and Prevention. 32, 10, p. 1402-1410 9 p.

Research output: Contribution to journal › Article › peer-review

MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming

Mohammed Ismail, W., Mazzone, A., Ghiraldini, F. G., Kaur, J., Bains, M., Munankarmy, A., Bagwell, M. S., Safgren, S. L., Moore-Weiss, J., Buciuc, M., Shimp, L., Leach, K. A., Duarte, L. F., Nagi, C. S., Carcamo, S., Chung, C. Y., Hasson, D., Dadgar, N., Zhong, J., Lee, J. H., & 5 othersCouch, F. J., Revzin, A., Ordog, T., Bernstein, E. & Gaspar-Maia, A., Dec 2023, In: Communications Biology. 6, 1, 215.

Research output: Contribution to journal › Article › peer-review

Open Access

Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis

AURORA US Network, Jan 2023, In: Nature Cancer. 4, 1, p. 128-147 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects

Belhadj, S., Khurram, A., Bandlamudi, C., Palou-Márquez, G., Ravichandran, V., Steinsnyder, Z., Wildman, T., Catchings, A., Kemel, Y., Mukherjee, S., Fesko, B., Arora, K., Mehine, M., Dandiker, S., Izhar, A., Petrini, J., Domchek, S., Nathanson, K. L., Brower, J., Couch, F., & 9 othersStadler, Z., Robson, M., Walsh, M., Vijai, J., Berger, M., Supek, F., Karam, R., Topka, S. & Offit, K., Jan 15 2023, In: Clinical Cancer Research. 29, 2, p. 422-431 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

PDJ amplicon in triple negative breast cancer

Roesler, A. S., Malasi, S., Koslosky, L., Hartmayer, P., Naab, T. J., Carter, J. M., Zahrieh, D., Hillman, D., Leon-Ferre, R. A., Couch, F. J., Goetz, M. P., Anderson, K. S., Pockaj, B. A. & Barrett, M. T., Dec 2023, In: Scientific reports. 13, 1, 618.

Research output: Contribution to journal › Article › peer-review

Open Access

Prognostic stratification of endometrial cancers with high microsatellite instability or no specific molecular profile

Gonzalez-Bosquet, J., Weroha, S. J., Bakkum-Gamez, J. N., Weaver, A. L., McGree, M. E., Dowdy, S. C., Famuyide, A. O., Kipp, B. R., Halling, K. C., Yadav, S., Couch, F. J. & Podratz, K. C., 2023, In: Frontiers in Oncology. 13, 1105504.

Research output: Contribution to journal › Article › peer-review

Open Access

Summary of the experiences, knowledge, medical management, and family communication of monoallelic MUTYH carriers

McKenna, D. B., Sanchez, P., Powers, J., Brower, J., Wang, L., Mueller, R., Symecko, H., Hamilton, J. G., Wildman, T., Domchek, S. M., Couch, F. J., Garber, J. E., Offit, K., Robson, M. E. & Katona, B. W., Apr 2023, In: Journal of Genetic Counseling. 32, 2, p. 342-350 9 p.

Research output: Contribution to journal › Article › peer-review

2022

A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis

RENACER, Mar 7 2022, In: EMBO Molecular Medicine. 14, 3, e14552.

Research output: Contribution to journal › Article › peer-review

Open Access

An integrative model for the comprehensive classification of BRCA1 and BRCA2 variants of uncertain clinical significance

Iversen, E. S., Lipton, G., Hart, S. N., Lee, K. Y., Hu, C., Polley, E. C., Pesaran, T., Yussuf, A., LaDuca, H., Chao, E., Karam, R., Goldgar, D. E., Couch, F. J. & Monteiro, A. N. A., Dec 2022, In: npj Genomic Medicine. 7, 1, 35.

Research output: Contribution to journal › Article › peer-review

Open Access

Assessment of small in-frame indels and C-terminal nonsense variants of BRCA1 using a validated functional assay

Nepomuceno, T. C., dos Santos, A. P. P., Fernandes, V. C., Elias, A. B. R., Gomes, T. T., Suarez-Kurtz, G., Iversen, E. S., Couch, F. J., Monteiro, A. N. A. & Carvalho, M. A., Dec 2022, In: Scientific reports. 12, 1, 16203.

Research output: Contribution to journal › Article › peer-review

Open Access

Bilateral Oophorectomy and the Risk of Breast Cancer in BRCA1 Mutation Carriers: A Reappraisal

the Hereditary Breast Cancer Clinical Study Group, Jul 2022, In: Cancer Epidemiology Biomarkers and Prevention. 31, 7, p. 1351-1358 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores

Barnes, D. R., Silvestri, V., Leslie, G., McGuffog, L., Dennis, J., Yang, X., Adlard, J., Agnarsson, B. A., Ahmed, M., Aittomaki, K., Andrulis, I. L., Arason, A., Arnold, N., Auber, B., Azzollini, J., Balmana, J., Barkardottir, R. B., Barrowdale, D., Barwell, J., Belotti, M., & 144 othersBenitez, J., Berthet, P., Boonen, S. E., Borg, A., Bozsik, A., Brady, A. F., Brennan, P., Brewer, C., Brunet, J., Bucalo, A., Buys, S. S., Caldes, T., Caligo, M. A., Campbell, I., Cassingham, H., Christensen, L. L., Cini, G., Claes, K. B. M., Cook, J., Coppa, A., Cortesi, L., Damante, G., Darder, E., Davidson, R., De La Hoya, M., De Leeneer, K., De Putter, R., Del Valle, J., Diez, O., Ding, Y. C., Domchek, S. M., Donaldson, A., Eason, J., Eeles, R., Engel, C., Evans, D. G., Feliubadalo, L., Fostira, F., Frone, M., Frost, D., Gallagher, D., Gehrig, A., Giraud, S., Glendon, G., Godwin, A. K., Goldgar, D. E., Greene, M. H., Gregory, H., Gross, E., Hahnen, E., Hamann, U., Hansen, T. V. O., Hanson, H., Hentschel, J., Horvath, J., Izatt, L., Izquierdo, A., James, P. A., Janavicius, R., Jensen, U. B., Johannsson, O. T., John, E. M., Kramer, G., Kroeldrup, L., Kruse, T. A., Lautrup, C., Lazaro, C., Lesueur, F., Lopez-Fernandez, A., Mai, P. L., Manoukian, S., Matrai, Z., Matricardi, L., Maxwell, K. N., Mebirouk, N., Meindl, A., Montagna, M., Monteiro, A. N., Morrison, P. J., Muranen, T. A., Murray, A., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Nguyen-Dumont, T., Niederacher, D., Olah, E., Olopade, O. I., Palli, D., Parsons, M. T., Pedersen, I. S., Peissel, B., Perez-Segura, P., Peterlongo, P., Petersen, A. H., Pinto, P., Porteous, M. E., Pottinger, C., Pujana, M. A., Radice, P., Ramser, J., Rantala, J., Robson, M., Rogers, M. T., Rønlund, K., Rump, A., Sanchez De Abajo, A. M., Shah, P. D., Sharif, S., Side, L. E., Singer, C. F., Stadler, Z., Steele, L., Stoppa-Lyonnet, D., Sutter, C., Tan, Y. Y., Teixeira, M. R., Teule, A., Thull, D. L., Tischkowitz, M., Toland, A. E., Tommasi, S., Toss, A., Trainer, A. H., Tripathi, V., Valentini, V., Van Asperen, C. J., Venturelli, M., Viel, A., Vijai, J., Walker, L., Wang-Gohrke, S., Wappenschmidt, B., Whaite, A., Zanna, I., Offit, K., Thomassen, M., Couch, F. J., Schmutzler, R. K., Simard, J., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C. & Ottini, L., Jan 1 2022, In: Journal of the National Cancer Institute. 114, 1, p. 109-122 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Breast Cancer Screening Strategies for Women with ATM, CHEK2, and PALB2 Pathogenic Variants: A Comparative Modeling Analysis

Lowry, K. P., Geuzinge, H. A., Stout, N. K., Alagoz, O., Hampton, J., Kerlikowske, K., De Koning, H. J., Miglioretti, D. L., Van Ravesteyn, N. T., Schechter, C., Sprague, B. L., Tosteson, A. N. A., Trentham-Dietz, A., Weaver, D., Yaffe, M. J., Yeh, J. M., Couch, F. J., Hu, C., Kraft, P., Polley, E. C., & 3 othersMandelblatt, J. S., Kurian, A. W. & Robson, M. E., Apr 2022, In: JAMA Oncology. 8, 4, p. 587-596 10 p.

Research output: Contribution to journal › Article › peer-review

CDK5RAP3, a New BRCA2 Partner That Regulates DNA Repair, Is Associated with Breast Cancer Survival

Minguillón, J., Ramírez, M. J., Rovirosa, L., Bustamante-Madrid, P., Camps-Fajol, C., De Garibay, G. R., Shimelis, H., Montanuy, H., Pujol, R., Hernandez, G., Bogliolo, M., Castillo, P., Soucy, P., Martrat, G., Gómez, A., Cuadras, D., García, M. J., Gayarre, J., Lázaro, C., Benítez, J., & 3 othersCouch, F. J., Angel Pujana, M. & Surrallés, J., Jan 1 2022, In: Cancers. 14, 2, 353.

Research output: Contribution to journal › Article › peer-review

Open Access

Classification of BRCA2 Variants of Uncertain Significance (VUS) Using an ACMG/AMP Model Incorporating a Homology-Directed Repair (HDR) Functional Assay

Hu, C., Susswein, L. R., Roberts, M. E., Yang, H., Marshall, M. L., Hiraki, S., Berkofsky-Fessler, W., Gupta, S., Shen, W., Dunn, C. A., Huang, H., Na, J., Domchek, S. M., Yadav, S., Monteiro, A. N. A., Polley, E. C., Hart, S. N., Hruska, K. S. & Couch, F. J., Sep 1 2022, In: Clinical Cancer Research. 28, 17, p. 3742-3751 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Common variants in breast cancer risk loci predispose to distinct tumor subtypes

NBCS Collaborators, ABCTB Investigators & kConFab/AOCS Investigators, Dec 1 2022, In: Breast Cancer Research. 24, 1, 2.

Research output: Contribution to journal › Article › peer-review

Open Access

Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

GEMO Study Collaborators, EMBRACE Collaborators, SWE-BRCA Investigators, KConFab investigators & HEBON Investigators, Dec 2022, In: Communications Biology. 5, 1, 1061.

Research output: Contribution to journal › Article › peer-review

Open Access

ECPPF (E2F1, CCNA2, POLE, PPP2R1A, FBXW7) stratification: Profiling high-risk subtypes of histomorphologically low-risk and treatment-insensitive endometrioid endometrial cancer

Gonzalez-Bosquet, J., John Weroha, S., Bakkum-Gamez, J. N., Weaver, A. L., McGree, M. E., Dowdy, S. C., Famuyide, A. O., Kipp, B. R., Halling, K. C., Yadav, S., Couch, F. J. & Podratz, K. C., Dec 2022, In: PloS one. 17, 12 December, e0278408.

Research output: Contribution to journal › Article › peer-review

Open Access

Erratum: Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk (European journal of human genetics : EJHG (2022) 30 3 (349-362))

GEMO Study Collaborators, GC-HBOC Study Collaborators, EMBRACE Collaborators, OPAL study group, AOCS Group, KConFab investigators, HEBON Investigators, OCAC Consortium & CIMBA Consortium, May 1 2022, In: European Journal of Human Genetics. 30, 5, p. 630-631 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Erratum: Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants (Genetics in Medicine (2022) 24(1) (119–129), (S1098360021011308), (10.1016/j.gim.2021.08.016))

ENIGMA Consortium and CIMBA Consortium, Oct 2022, In: Genetics in Medicine. 24, 10, p. 2208 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer

Aspros, K. G. M., Carter, J. M., Hoskin, T. L., Suman, V. J., Subramaniam, M., Emch, M. J., Ye, Z., Sun, Z., Sinnwell, J. P., Thompson, K. J., Tang, X., Rodman, E. P. B., Wang, X., Nelson, A. W., Chernukhin, I., Hamdan, F. H., Bruinsma, E. S., Carroll, J. S., Fernandez-Zapico, M. E., Johnsen, S. A., & 7 othersKalari, K. R., Huang, H., Leon-Ferre, R. A., Couch, F. J., Ingle, J. N., Goetz, M. P. & Hawse, J. R., Dec 2022, In: npj Breast Cancer. 8, 1, 20.

Research output: Contribution to journal › Article › peer-review

Open Access

Factors Associated With Physical Activity Levels in Patients With Breast Cancer

Marell, P. S., Vierkant, R. A., Olson, J. E., Herrmann, J., Larson, N., LeBrasseur, N. K., D'Andre, S. D., Cheville, A. L., Barksdale, T., Loprinzi, C. L., Couch, F. & Ruddy, K. J., Oct 2022, In: Oncologist. 27, 10, p. E811-E814

Research output: Contribution to journal › Article › peer-review

Open Access

First international workshop of the ATM and cancer risk group (4-5 December 2019)

Spanish ATM working group, GC-HBOC & CARRIERS and Ambry Groups, Apr 2022, In: Familial Cancer. 21, 2, p. 211-227 17 p.

Research output: Contribution to journal › Review article › peer-review

Genetic Risk of Second Primary Cancer in Breast Cancer Survivors: The Multiethnic Cohort Study

Chen, F., Park, S. L., Wilkens, L. R., Wan, P., Hart, S. N., Hu, C., Yadav, S., Couch, F. J., Conti, D. V., de Smith, A. J. & Haiman, C. A., Sep 15 2022, In: Cancer research. 82, 18, p. 3201-3208 8 p.

Research output: Contribution to journal › Article › peer-review

Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci

NBCS Investigators, Dec 2022, In: Breast Cancer Research. 24, 1, 27.

Research output: Contribution to journal › Article › peer-review

Open Access

Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women

Wang, X., Kapoor, P. M., Auer, P. L., Dennis, J., Dunning, A. M., Wang, Q., Lush, M., Michailidou, K., Bolla, M. K., Aronson, K. J., Murphy, R. A., Brooks-Wilson, A., Lee, D. G., Cordina-Duverger, E., Guénel, P., Truong, T., Mulot, C., Teras, L. R., Patel, A. V., Dossus, L., & 60 othersKaaks, R., Hoppe, R., Lo, W. Y., Brüning, T., Hamann, U., Czene, K., Gabrielson, M., Hall, P., Eriksson, M., Jung, A., Becher, H., Couch, F. J., Larson, N. L., Olson, J. E., Ruddy, K. J., Giles, G. G., MacInnis, R. J., Southey, M. C., Le Marchand, L., Wilkens, L. R., Haiman, C. A., Olsson, H., Augustinsson, A., Krüger, U., Wagner, P., Scott, C., Winham, S. J., Vachon, C. M., Perou, C. M., Olshan, A. F., Troester, M. A., Hunter, D. J., Eliassen, H. A., Tamimi, R. M., Brantley, K., Andrulis, I. L., Figueroa, J., Chanock, S. J., Ahearn, T. U., García-Closas, M., Evans, G. D., Newman, W. G., van Veen, E. M., Howell, A., Wolk, A., Håkansson, N., Anton-Culver, H., Ziogas, A., Jones, M. E., Orr, N., Schoemaker, M. J., Swerdlow, A. J., Kitahara, C. M., Linet, M., Prentice, R. L., Easton, D. F., Milne, R. L., Kraft, P., Chang-Claude, J. & Lindström, S., Dec 2022, In: Scientific reports. 12, 1, 6199.

Research output: Contribution to journal › Article › peer-review

Open Access

Incorporating progesterone receptor expression into the PREDICT breast prognostic model

ABCTB Investigators, KConFab investigators & KConFab investigators, Sep 2022, In: European Journal of Cancer. 173, p. 178-193 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Influence of Cancer Susceptibility Gene Mutations and ABO Blood Group of Pancreatic Cancer Probands on Concomitant Risk to First-Degree Relatives

Antwi, S. O., Rabe, K. G., Bamlet, W. R., Meyer, M., Chandra, S., Fagan, S. E., Hu, C., Couch, F. J., McWilliams, R. R., Oberg, A. L. & Petersen, G. M., Feb 2022, In: Cancer Epidemiology Biomarkers and Prevention. 31, 2, p. 372-381 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Luminal androgen receptor breast cancer subtype and investigation of the microenvironment and neoadjuvant chemotherapy response

Thompson, K. J., Leon-Ferre, R. A., Sinnwell, J. P., Zahrieh, D. M., Suman, V. J., Metzger, F. O., Asad, S., Stover, D. G., Carey, L., Sikov, W. M., Ingle, J. N., Liu, M. C., Carter, J. M., Klee, E. W., Weinshilboum, R. M., Boughey, J. C., Wang, L., Couch, F. J., Goetz, M. P. & Kalari, K. R., Jun 1 2022, In: NAR Cancer. 4, 2, zcac018.

Research output: Contribution to journal › Article › peer-review

Open Access

Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities

Cosgrove, N., Varešlija, D., Keelan, S., Elangovan, A., Atkinson, J. M., Cocchiglia, S., Bane, F. T., Singh, V., Furney, S., Hu, C., Carter, J. M., Hart, S. N., Yadav, S., Goetz, M. P., Hill, A. D. K., Oesterreich, S., Lee, A. V., Couch, F. J. & Young, L. S., Dec 2022, In: Nature communications. 13, 1, 514.

Research output: Contribution to journal › Article › peer-review

Open Access

Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

Strand, S. H., Rivero-Gutiérrez, B., Houlahan, K. E., Seoane, J. A., King, L. M., Risom, T., Simpson, L. A., Vennam, S., Khan, A., Cisneros, L., Hardman, T., Harmon, B., Couch, F., Gallagher, K., Kilgore, M., Wei, S., DeMichele, A., King, T., McAuliffe, P. F., Nangia, J., & 32 othersLee, J., Tseng, J., Storniolo, A. M., Thompson, A. M., Gupta, G. P., Burns, R., Veis, D. J., DeSchryver, K., Zhu, C., Matusiak, M., Wang, J., Zhu, S. X., Tappenden, J., Ding, D. Y., Zhang, D., Luo, J., Jiang, S., Varma, S., Anderson, L., Straub, C., Srivastava, S., Curtis, C., Tibshirani, R., Angelo, R. M., Hall, A., Owzar, K., Polyak, K., Maley, C., Marks, J. R., Colditz, G. A., Hwang, E. S. & West, R. B., Dec 12 2022, In: Cancer cell. 40, 12, p. 1521-1536.e7

Research output: Contribution to journal › Article › peer-review

Open Access

Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study

Dixon-Suen, S. C., Lewis, S. J., Martin, R. M., English, D. R., Boyle, T., Giles, G. G., Michailidou, K., Bolla, M. K., Wang, Q., Dennis, J., Lush, M., Investigators, A., Ahearn, T. U., Ambrosone, C. B., Andrulis, I. L., Anton-Culver, H., Arndt, V., Aronson, K. J., Augustinsson, A., Auvinen, P., & 138 othersFreeman, L. E. B., Becher, H., Beckmann, M. W., Behrens, S., Bermisheva, M., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bonanni, B., Brenner, H., Brüning, T., Buys, S. S., Camp, N. J., Campa, D., Canzian, F., Castelao, J. E., Cessna, M. H., Chang-Claude, J., Chanock, S. J., Clarke, C. L., Conroy, D. M., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Devilee, P., Dörk, T., Dwek, M., Eccles, D. M., Eliassen, A. H., Engel, C., Eriksson, M., Evans, D. G., Fasching, P. A., Fletcher, O., Flyger, H., Fritschi, L., Gabrielson, M., Gago-Dominguez, M., García-Closas, M., García-Sáenz, J. A., Goldberg, M. S., Guénel, P., Gündert, M., Hahnen, E., Haiman, C. A., Häberle, L., Håkansson, N., Hall, P., Hamann, U., Hart, S. N., Harvie, M., Hillemanns, P., Hollestelle, A., Hooning, M. J., Hoppe, R., Hopper, J., Howell, A., Hunter, D. J., Jakubowska, A., Janni, W., John, E. M., Jung, A., Kaaks, R., Keeman, R., Kitahara, C. M., Koutros, S., Kraft, P., Kristensen, V. N., Kubelka-Sabit, K., Kurian, A. W., Lacey, J. V., Lambrechts, D., Le Marchand, L., Lindblom, A., Loibl, S., Lubiński, J., Mannermaa, A., Manoochehri, M., Margolin, S., Martinez, M. E., Mavroudis, D., Menon, U., Mulligan, A. M., Murphy, R. A., Collaborators, N., Nevanlinna, H., Nevelsteen, I., Newman, W. G., Offit, K., Olshan, A. F., Olsson, H., Orr, N., Patel, A., Peto, J., Plaseska-Karanfilska, D., Presneau, N., Rack, B., Radice, P., Rees-Punia, E., Rennert, G., Rennert, H. S., Romero, A., Saloustros, E., Sandler, D. P., Schmidt, M. K., Schmutzler, R. K., Schwentner, L., Scott, C., Shah, M., Shu, X. O., Simard, J., Southey, M. C., Stone, J., Surowy, H., Swerdlow, A. J., Tamimi, R. M., Tapper, W. J., Taylor, J. A., Terry, M. B., Tollenaar, R. A. E. M., Troester, M. A., Truong, T., Untch, M., Vachon, C. M., Joseph, V., Wappenschmidt, B., Weinberg, C. R., Wolk, A., Yannoukakos, D., Zheng, W., Ziogas, A., Dunning, A. M., Pharoah, P. D. P., Easton, D. F., Milne, R. L. & Lynch, B. M., Sep 6 2022, In: British journal of sports medicine. 56, 20, p. 1157-1170 14 p.

Research output: Contribution to journal › Article › peer-review

Polygenic risk modeling for prediction of epithelial ovarian cancer risk

GEMO Study Collaborators, GC-HBOC Study Collaborators, EMBRACE Collaborators, OPAL study group, AOCS Group, KConFab investigators, HEBON Investigators, The OCAC Consortium & the Cimba Consortium, Mar 2022, In: European Journal of Human Genetics. 30, 3, p. 349-362 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Rare germline copy number variants (CNVs) and breast cancer risk

NBCS Collaborators, CTS Consortium, ABCTB Investigators & kConFab/AOCS Investigators, Dec 2022, In: Communications Biology. 5, 1, 65.

Research output: Contribution to journal › Article › peer-review

Open Access

Rare germline variants in PALB2 and BRCA2 in familial and sporadic chordoma

Xia, B., Biswas, K., Foo, T. K., Gomes, T. T., Riedel-Topper, M., Southon, E., Kang, Z., Huo, Y., Reid, S., Stauffer, S., Zhou, W., Zhu, B., Koka, H., Yepes, S., Brodie, S. A., Jones, K., Vogt, A., Carter, B., Freedman, N. D., Hicks, B., & 9 othersYeager, M., Chanock, S. J., Couch, F., Parry, D. M., Monteiro, A. N., Goldstein, A. M., Carvalho, M. A., Sharan, S. K. & Yang, X. R., Oct 1 2022, In: Human mutation. 43, 10, p. 1396-1407 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Reproductive risk factors associated with breast cancer in young women by molecular subtype

Ruddy, K. J., Vierkant, R. A., Jahan, N., Higgins, A., Partridge, A., Larson, N., Radisky, D. C., Couch, F., Olson, J. & Sherman, M. E., Dec 2022, In: Breast. 66, p. 272-277 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants

ENIGMA Consortium & CIMBA Consortium, Jan 2022, In: Genetics in Medicine. 24, 1, p. 119-129 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Surveillance mammography after treatment for male breast cancer

Yadav, S., Sangaralingham, L., Payne, S. R., Giridhar, K. V., Hieken, T. J., Boughey, J. C., Mutter, R. W., Hawse, J. R., Jimenez, R. E., Freedman, R. A., Khanani, S., Couch, F. J., Vachon, C., Shah, N., Leon-Ferre, R. A. & Ruddy, K. J., Aug 2022, In: Breast Cancer Research and Treatment. 194, 3, p. 693-698 6 p.

Research output: Contribution to journal › Article › peer-review

Surveillance mammography in older breast cancer survivors: Current practice patterns and patient perceptions

Karam, D., Vierkant, R. A., Ehlers, S., Freedman, R. A., Austin, J., Khanani, S., Larson, N. L., Loprinzi, C. L., Couch, F., Olson, J. E. & Ruddy, K. J., Sep 2022, In: Journal of Geriatric Oncology. 13, 7, p. 1038-1042 5 p.

Research output: Contribution to journal › Article › peer-review

The risks of cancer in older women with BRCA pathogenic variants: How far have we come?

Metcalfe, K. A., Gronwald, J., Tung, N. M., McCuaig, J. M., Eisen, A., Elser, C., Foulkes, W. D., Neuhausen, S. L., Senter, L., Moller, P., Bordeleau, L., Fruscio, R., Velsher, L., Zakalik, D., Olopade, O. I., Eng, C., Pal, T., Cullinane, C. A., Couch, F. J., Kotsopoulos, J., & 3 othersSun, P., Lubinski, J. & Narod, S. A., Dec 26 2022, In: Cancer. 129, 6, p. 901-907 7 p.

Research output: Contribution to journal › Article › peer-review

Tissue methylated DNA markers for sporadic pancreatic cancer are strongly associated with familial and genetically predisposed pancreatic cancer

Majumder, S., Taylor, W. R., Foote, P. H., Gysbers, B. J., Cao, X., Mahoney, D. W., Burger, K. N., Doering, K. A., Graham, R. P., Couch, F. J., Petersen, G. M. & Kisiel, J. B., 2022, (Accepted/In press) In: Pancreatology.

Research output: Contribution to journal › Article › peer-review

Fergus J Couch, PhD

Research output

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