Projects per year
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Collaborations and top research areas from the last five years
Projects
- 13 Finished
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Exploiting new approaches for selective inhibition of trypsins
Radisky, E. S. (PI)
1/1/22 → 11/30/25
Project: Research project
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Proteolysis in the Pathogenesis of ARDS
Downey, G. P. (PI), Radisky, D. C. (CoPI) & Radisky, E. S. (CoPI)
National Heart, Lung, and Blood Institute
12/22/21 → 11/30/25
Project: Research project
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Engineering tissue inhibitor of metalloproteinases-2 (TIMP-2) for triple negative breast cancer therapy
Radisky, E. S. (PI)
3/1/21 → 2/28/26
Project: Research project
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Targeting the IL-6 - SPINK1 regulatory axis in ovarian clear cell carcinoma
Radisky, E. S. (PI)
4/1/18 → 7/31/20
Project: Research project
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Targeting MMP-9 for breast cancer therapy (R21 CA205471 Resubmission)
Radisky, E. S. (PI)
7/1/16 → 12/31/18
Project: Research project
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Engineering selective amyloid precursor protein inhibitors by machine learning and deep mutational scanning
Meiri, R., Reuveni, O., Levi, M., Radisky, E. S., Papo, N. & Orenstein, Y., Aug 2026, In: Protein Science. 35, 8, e70712.Research output: Contribution to journal › Article › peer-review
Open Access -
Modifying inhibitor specificity for homologous enzymes by machine learning
Gozlan, D. S., Meiri, R., Shapira, G., Coban, M., Radisky, E. S., Orenstein, Y. & Papo, N., Feb 2026, In: FEBS Journal. 293, 4, p. 1007-1023 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
PRSS23 promotes ovarian cancer peritoneal dissemination independent of protease activity
Akhtar, S., Coban, M., Miller, E., Hockla, A., Maina, E., Mehner, C., Ilic, S., Papo, N., Radisky, D. C. & Radisky, E. S., Jun 2026, In: Journal of Biological Chemistry. 302, 6, 111450.Research output: Contribution to journal › Article › peer-review
Open Access -
Therapeutic potential of inhibitors of gelatinases MMP-2 and MMP-9 for the treatment of breast cancer
Shoari, A., Coban, M. A. & Radisky, E. S., Jul 2026, In: FEBS Journal. 293, 13, p. 4014-4042 29 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Directed evolution of metalloproteinase inhibitor TIMP-1 for selective inhibition of MMP-9 exploits catalytic and fibronectin domain interactions
Shoari, A., Coban, M. A., Hockla, A., Rezhdo, A., Dimesa, A. M., Raeeszadeh-Sarmazdeh, M., Van Deventer, J. A. & Radisky, E. S., Jun 2025, In: Journal of Biological Chemistry. 301, 6, 110258.Research output: Contribution to journal › Article › peer-review
Open Access