Projects per year
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Dive into the research topics where Evette S Radisky is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Exploiting new approaches for selective inhibition of trypsins
Radisky, E. S. (PI)
National Institute of General Medical Sciences
1/1/22 → 11/30/25
Project: Research project
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Proteolysis in the Pathogenesis of ARDS
Downey, G. P. (PI), Radisky, D. C. (CoPI) & Radisky, E. S. (CoPI)
National Heart, Lung, and Blood Institute
12/22/21 → 11/30/25
Project: Research project
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Engineering tissue inhibitor of metalloproteinases-2 (TIMP-2) for triple negative breast cancer therapy
Radisky, E. S. (PI)
3/1/21 → 2/28/26
Project: Research project
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Engineering selective inhibition of metalloproteinases by tissue inhibitors of metalloproteinases (R01 GM132100 RESUB - *TIMPs)
Radisky, E. S. (PI)
National Institute of General Medical Sciences
4/1/20 → 12/31/23
Project: Research project
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Targeting the IL-6 - SPINK1 regulatory axis in ovarian clear cell carcinoma
Radisky, E. S. (PI)
4/1/18 → 7/31/20
Project: Research project
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Directed evolution of metalloproteinase inhibitor TIMP-1 for selective inhibition of MMP-9 exploits catalytic and fibronectin domain interactions
Shoari, A., Coban, M. A., Hockla, A., Rezhdo, A., Dimesa, A. M., Raeeszadeh-Sarmazdeh, M., Van Deventer, J. A. & Radisky, E. S., Jun 2025, In: Journal of Biological Chemistry. 301, 6, 110258.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of an autoinhibited conformation in mesotrypsin reveals a strategy for selective serine protease inhibition
Coban, M., Gokara, M., Forero Vargas, L. M., Tanzer, S. D., Zhou, S. X., Hockla, A., Sankaran, B., Caulfield, T. R. & Radisky, E. S., Jul 4 2025, In: Science Advances. 11, 27, eadu9129.Research output: Contribution to journal › Article › peer-review
Open Access -
Matrix metalloproteinase-driven epithelial-mesenchymal transition: implications in health and disease
Khalili-Tanha, G., Radisky, E. S., Radisky, D. C. & Shoari, A., Dec 2025, In: Journal of Translational Medicine. 23, 1, 436.Research output: Contribution to journal › Review article › peer-review
Open Access -
Modifying inhibitor specificity for homologous enzymes by machine learning
Gozlan, D. S., Meiri, R., Shapira, G., Coban, M., Radisky, E. S., Orenstein, Y. & Papo, N., 2025, (Accepted/In press) In: FEBS Journal.Research output: Contribution to journal › Article › peer-review
Open Access -
Engineered TIMP2 with narrow MMP-9 specificity is an effective inhibitor of invasion and proliferation of triple-negative breast cancer cells
Rotenberg, N., Feldman, M., Shirian, J., Hockla, A., Radisky, E. S. & Shifman, J. M., Nov 2024, In: Journal of Biological Chemistry. 300, 11, 107867.Research output: Contribution to journal › Article › peer-review
Open Access