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Dive into the research topics where Edward B Leof is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Mayo Clinic Hepatobiliary SPORE
Mc Niven, M. M. A. (PI), Alberts, S. R. (CoPI), Wang, C. C. (CoPI), Gores, G. J. (CoPI), Leof, E. B. (CoPI), Roberts, L. R. (CoPI), Mandrekar, S. J. (CoPI), Smoot, R. (CoPI), Simon, S. M. (CoPI), Torbenson, M. (CoPI), Vile, R. G. (CoPI) & Yin, V. (CoPI)
9/10/18 → 8/31/25
Project: Research project
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Developmental Research Program
Leof, E. B. (PI), Mc Niven, M. A. (PI) & Mc Niven, M. M. A. (PI)
9/1/18 → 8/31/23
Project: Research project
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TGF Beta Receptor Dynamics
Leof, E. B. (PI)
National Institute of General Medical Sciences
5/1/09 → 4/30/19
Project: Research project
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Symposium on Extracellular and Membrane Proteases in Cell Signaling
Nilsen-hamilton, M. (PI), Blobel, G. G. (CoPI), Hung, M. C. (CoPI), Leof, E. B. (CoPI), Matrisian, L. M. (CoPI), Overall, C. M. (CoPI) & Trejo, J. (CoPI)
9/4/08 → 8/31/09
Project: Research project
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CAF, A COACTIVATOR OF FOS, AND BREAST CANCER
Leof, E. B. (PI) & Getz, M. J. (CoPI)
12/17/97 → 3/30/01
Project: Research project
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A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila
Peterson, A. J., Murphy, S. J., Mundt, M. G., Shimell, M. J., Leof, E. B. & O’Connor, M. B., May 2022, In: PLoS biology. 20, 5, e3001660.Research output: Contribution to journal › Article › peer-review
Open Access -
Aurora-A kinase oncogenic signaling mediates TGF-β-induced triple-negative breast cancer plasticity and chemoresistance
Jalalirad, M., Haddad, T. C., Salisbury, J. L., Radisky, D., Zhang, M., Schroeder, M., Tuma, A., Leof, E., Carter, J. M., Degnim, A. C., Boughey, J. C., Sarkaria, J., Yu, J., Wang, L., Liu, M. C., Zammataro, L., Malatino, L., Galanis, E., Ingle, J. N. & Goetz, M. P. & 1 others, , Apr 8 2021, In: Oncogene. 40, 14, p. 2509-2523 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Vardenafil activity in lung fibrosis and in vitro synergy with nintedanib
Bourne, M. H., Kottom, T. J., Hebrink, D. M., Choudhury, M., Leof, E. B. & Limper, A. H., Dec 2021, In: Cells. 10, 12, 3502.Research output: Contribution to journal › Article › peer-review
Open Access -
IPF pathogenesis is dependent upon TGFβ induction of IGF-1
Hernandez, D. M., Kang, J. H., Choudhury, M., Andrianifahanana, M., Yin, X., Limper, A. H. & Leof, E. B., Apr 1 2020, In: FASEB Journal. 34, 4, p. 5363-5388 26 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
SIRT7-mediated modulation of glutaminase 1 regulates TGF-β-induced pulmonary fibrosis
Choudhury, M., Yin, X., Schaefbauer, K. J., Kang, J. H., Roy, B., Kottom, T. J., Limper, A. H. & Leof, E. B., Jul 1 2020, In: FASEB Journal. 34, 7, p. 8920-8940 21 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations