Allergy, Asthma and Clinical Immunology

Projects

Projects per year 1985 2000 2001 2012 2014 2018 2024

• 8 Active
• 21 Finished

Projects per year

Search results

• Active

  Targeting a Defined Surgical Stress-Induced Inflammatory Pathway to Improve Peri-Operative Outcomes

  Krupnick, A. S. & Jacobsen, E.

  National Heart, Lung, and Blood Institute

  1/1/23 → 12/31/23

  Project: Research project

  • Eosinophils 100%
  • Lung 67%
  • Interleukin-33 31%
  • Eosinophilia 25%
  • Cytokines 21%

• Allergen-induced extracellular DNA in type 2 immunity

  Kita, H. & O'grady, S. S. M.

  National Institute of Allergy and Infectious Diseases

  9/21/22 → 7/31/24

  Project: Research project

  • Allergens 100%
  • Immunity 56%
  • DNA 53%
  • Epithelial Cells 31%
  • Caspase 3 19%

• Epigenetic mechanisms of carcinogenesis by Parvimonas micra, an oral cavity commensal turned colon cancer pathogen

  Khazaie, K., Gounari, F. & Staley, C.

  National Cancer Institute

  9/13/21 → 8/31/24

  Project: Research project

  • Colonic Neoplasms 100%
  • Epigenomics 96%
  • Mouth 94%
  • Colorectal Neoplasms 87%
  • Carcinogenesis 84%

• Enhancing Antitumor Immunity with PP4 Inhibition and Chemoimmunotherapy

  Curtis, M.

  Congressionally Directed Medical Research Programs

  1/1/20 → …

  Project: Research project

  • protein phosphatase 4 100%
  • Ovarian Neoplasms 67%
  • Immunity 32%
  • Immunotherapy 30%
  • protein phosphatase inhibitor-4 13%

• The Role of Eosinophils in the Lung Allograft

  Krupnick, A. S., Jacobsen, E. E. A., Jacobsen, E. & Krupnick, A. S.

  2/1/19 → 1/31/24

  Project: Research project

  • Eosinophils 100%
  • Allografts 32%
  • Lung 31%
  • Transplantation Tolerance 30%
  • Immunosuppression 20%

• Mechanisms of Allergen-induced Type 2 Immunity

  Kita, H.

  5/1/18 → 4/30/24

  Project: Research project

  • Allergens 100%
  • Helper-Inducer T-Lymphocytes 49%
  • Immunity 47%
  • Immunoglobulin E 26%
  • Mucous Membrane 23%

• Mechanisms of IL-33 secretion in allergic diseases

  Kita, H., O'Grady, S. M. & O'Grady, S. M.

  12/16/16 → 1/31/24

  Project: Research project

  • Interleukin-33 100%
  • Allergens 46%
  • Acetylcholine 45%
  • Alternaria 23%
  • Epithelial Cells 17%

• How beta-catenin expands Foxp3+RORgammat+ Pro-inflammatoryT-regulatory cells - Renewal

  Gounari, F. & Khazaie, K.

  National Institute of Allergy and Infectious Diseases

  7/1/14 → 6/30/24

  Project: Research project

  • Nuclear Receptor Subfamily 1, Group F, Member 3 100%
  • Catenins 90%
  • Regulatory T-Lymphocytes 55%
  • Chromatin 19%
  • Genetic Enhancer Elements 13%
• Finished

  Step down of asthma biologics in real-world practice settings

  Rank, M. A.

  National Heart, Lung, and Blood Institute

  8/15/18 → 8/31/21

  Project: Research project

  • Asthma 100%
  • Biological Products 73%
  • Omalizumab 24%
  • reslizumab 18%
  • mepolizumab 16%

• Imaging Functionally Distinct Eosinophil Subtypes Within Tissue Biopsies Using Gene Expression Profiling and an In Situ Hybridization Approach based on a Concurrent Multiple RNA Targeting Strategy

  Jacobsen, E.

  National Institute of Allergy and Infectious Diseases

  12/20/17 → 10/31/20

  Project: Research project

  • Eosinophils 100%
  • Gene Expression Profiling 55%
  • In Situ Hybridization 54%
  • RNA 39%
  • Biopsy 37%

• Airway Sensory Nerves in Asthma

  Jacoby, D. B., Jacobsen, E. & Lee, J. J.

  9/1/14 → 4/30/19

  Project: Research project

  • Eosinophils 100%
  • Bronchoconstriction 63%
  • Asthma 46%
  • Reflex 30%
  • Eosinophil Peroxidase 13%

• DC-ASGPR as Novel Target for Controlling GVHD and Allograft Rejection

  Oh, S. & Oh, S.

  National Institute of Allergy and Infectious Diseases

  4/1/14 → 3/31/21

  Project: Research project

  • Dendritic Cells 100%
  • Graft vs Host Disease 99%
  • Allografts 74%
  • Isoantigens 39%
  • Immunosuppression 39%

• Role of Alcohol and Circadian Disruption in Inflammation and Colon Cancer

  Keshavarzian, A. & Khazaie, K.

  National Institute on Alcohol Abuse and Alcoholism

  2/5/14 → 1/31/21

  Project: Research project

  • Colonic Neoplasms 100%
  • Alcohols 97%
  • Circadian Rhythm 95%
  • Inflammation 82%
  • Shift Work Schedule 61%

• Bending the asthma cost curve: Is optimizing medication the answer?

  Rank, M. A.

  Agency for Healthcare Research and Quality

  9/30/13 → 9/29/14

  Project: Research project

  • Asthma 100%
  • Costs and Cost Analysis 52%
  • Health Expenditures 41%
  • Disease Management 13%
  • Chronic Disease 10%

• The Pathogenesis of Chronic Rhinosinusitis

  Kita, H.

  7/10/12 → 6/30/14

  Project: Research project

  • Interleukin-33 100%
  • Uric Acid 74%
  • Inflammation 43%
  • Asthma 24%
  • Mucous Membrane 16%

• Pro-inflammatory T-regulatory Cells in Colon Cancer

  Khazaie, K.

  5/15/12 → 3/31/18

  Project: Research project

  • Regulatory T-Lymphocytes 100%
  • Colonic Neoplasms 47%
  • Inflammation 28%
  • Neoplasms 20%
  • T-Lymphocytes 6%

• Eosinophil-nerve Interactions in Mouse Models of Dermatitis

  Jacobsen, E., Jacoby, D. B. & Lee, J. J.

  4/1/12 → 3/31/16

  Project: Research project

  • Eosinophils 100%
  • Dermatitis 47%
  • Skin 33%
  • Pruritus 17%
  • Gene Knock-In Techniques 14%

• Planning a Multicenter Oral Itraconazole Trial in Chronic Rhinosinusitis Patients

  Kita, H.

  4/1/07 → 2/28/09

  Project: Research project

  • Itraconazole 100%
  • Clinical Trials 54%
  • Nasal Polyps 53%
  • Fungal Antigens 34%
  • National Institute of Allergy and Infectious Diseases (U.S.) 32%

• Mechanisms of Eosinophilic Inflammation in Human Disease

  Kita, H.

  4/1/05 → 8/31/14

  Project: Research project

  • Interleukin-33 100%
  • Helper-Inducer T-Lymphocytes 75%
  • Asthma 73%
  • Allergens 59%
  • Lung 55%

• Mechanisms of Eosinophilic Inflammation in Human Asthma

  Kita, H., Gleich, G. J., O'Grady, S. M. & E. Wylam, M.

  9/10/01 → 6/30/07

  Project: Research project

  • Asthma 100%
  • Eosinophils 38%
  • Inflammation 34%
  • Eosinophil Granule Proteins 33%
  • Bronchial Hyperreactivity 28%

• The Pathogenesis of Chronic Rhinosinusitis

  Kita, H.

  3/1/01 → 7/9/12

  Project: Research project

  • Fungi 100%
  • Alternaria 79%
  • Inflammation 32%
  • Blood Cells 30%
  • Fungal Spores 25%

• Eosinophil Activities in Murine Models of Lung Disease

  Jacobsen, E. & Lee, J. J.

  9/30/00 → 1/31/19

  Project: Research project

  • Eosinophils 100%
  • Allergens 32%
  • T-Lymphocytes 26%
  • Adrenal Cortex Hormones 20%
  • Inflammation 20%

• Mechanisms Of Eosinophil Degranulation in Human Disease

  Kita, H.

  3/15/00 → 7/31/12

  Project: Research project

  • Alternaria 100%
  • Eosinophils 67%
  • Asthma 40%
  • Natural Killer Cells 24%
  • Inflammation 20%

• MECHANISMS OF EOSINOPHIL ASSOCIATED INFLAMATION

  Gleich, G. J., Patel, A. A., Gleich, G. G. J., Kita, H., Leiferman, K. M. & Leibson, P. P. J.

  9/30/97 → 8/31/01

  Project: Research project

  • Interleukin-5 100%
  • Natural Killer Cells 58%
  • Eosinophils 43%
  • Th2 Cells 21%
  • Inflammation 21%

• INTEGRINS IN EOSINOPHILIC INFLAMMATION

  Kita, H.

  10/1/96 → 9/30/98

  Project: Research project

• MECHANISMS OF EOSINOPHIL DEGRANULATION

  Kita, H.

  5/1/94 → 3/14/00

  Project: Research project

  • Eosinophils 100%
  • Ambrosia 15%
  • Allergens 14%
  • In Vitro Techniques 13%
  • Blood Cells 12%

• MECHANISMS OF EOSINOPHIL-ASSOCIATED INFLAMMATION

  Gleich, G. J., Kita, H., Leiferman, K. M., Rohrbach, M. S., Snyder, L. & Gleich, G. G. J.

  8/1/93 → 7/31/96

  Project: Research project

  • Eosinophils 100%
  • Eosinophil Granule Proteins 14%
  • Asthma 13%
  • Cell Adhesion Molecules 9%
  • Immune System Diseases 9%

• MECHANISM OF EOSINOPHIL ACTIVATION IN HUMAN DISEASE

  Kita, H.

  10/1/92 → 9/30/96

  Project: Research project

  • Eosinophils 100%
  • Cytokines 19%
  • Secretagogues 14%
  • Immunoglobulin E 7%
  • In Vitro Techniques 6%

• Training Grant in Allergic Diseases

  Kita, H. & Gleich, G. G. J.

  National Institute of Allergy and Infectious Diseases

  9/1/85 → 1/31/19

  Project: Research project

  • trainee 100%
  • Asthma 50%
  • applicant 28%
  • renewal application 28%
  • training program 24%